1001909-49-4Relevant academic research and scientific papers
Total synthesis of (-)-2-epi-lentiginosine by use of chiral 5-hydroxy-1,5-dihydropyrrol-2-one as a building block
Muramatsu, Takayuki,Yamashita, Sho,Nakamura, Yumiko,Suzuki, Masahisa,Mase, Nobuyuki,Yoda, Hidemi,Takabe, Kunihiko
, p. 8956 - 8959 (2007)
We have developed a practical synthesis of the chiral lactam as a new chiral building block for alkaloid synthesis. Lipase-catalyzed kinetic resolution of hydroxylactam 8, followed by isolation-racemization of the chiral acetoxylactam 9 provided the optic
