100221-39-4Relevant academic research and scientific papers
Synthesis and NMR studies of methyl 3-O-[(R)- and (S)-1-carboxyethyl]-α-D-gluco-, galacto- and manno- pyranosides
Andersson, Lars,Kenne, Lennart
, p. 157 - 164 (2007/10/03)
The title compounds were prepared by condensation of a suitably protected monosaccharide and (R)- or (S)-2-chloropropionic acid followed by removal of the protecting groups. Characterisation by 1H and 13C NMR spectroscopy and NOE difference experiments revealed both chemical shift and enhancement differences between the diastereomers which could be used in determination of the absolute configuration of the 1-carboxyethyl group. Copyright (C) 1998 Elsevier Science Ltd.
2-Substituted methyl alpha-D-galactopyranosides: synthesis and binding affinity for the A and B subunits of the Griffonia simplicifolia I isolectins.
Kaifu,Plantefaber,Goldstein
, p. 37 - 49 (2007/10/02)
The binding affinities of the N-acetyl, N-trifluoroacetyl, N-propionyl, N-formyl, N-benzoyl, N-p-nitrobenzoyl, N-p-aminobenzoyl, and N-methyl derivatives of methyl 2-amino-2-deoxy-alpha-D-galactopyranoside and the 2-O-acetyl, -benzoyl, -benzyl, and -methyl derivatives of methyl alpha-D-galactopyranoside for the A and B subunits of the Griffonia simplicifolia I isolectins have been determined by hapten inhibition analysis of a galactomannan-isolectin precipitation system. Models for these carbohydrate-protein interactions are presented together with an interpretation of the results on the basis of electronic and steric effects.
ALKYLATION OF METHYL 4,6-O-BENZYLIDENE-α-D-GALACTOPYRANOSIDE
Grishkovets, V. I.,Chirva, V. Ya.
, p. 25 - 28 (2007/10/02)
The partial alkylation of methyl 4,6-benzylidene-α-D-galactopyranoside in dimethylformamide and dimethyl sulfoxide in the presence of barium oxide and hydroxide is described.It has been shown that methylation and benzylation lead predominantly to the 3-al
