1002331-75-0Relevant academic research and scientific papers
γ-aminobutyric acid amides of nortriptyline and fluoxetine display improved pain suppressing activity
Rephaeli, Ada,Gil-Ad, Irit,Aharoni, Ana,Tarasenko, Igor,Tarasenko, Nataly,Geffen, Yona,Halbfinger, Efrat,Nisemblat, Yotam,Weizman, Abraham,Nudelman, Abraham
experimental part, p. 3010 - 3017 (2010/02/28)
The GABA amides of the antidepressants nortriptyline and fluoxetine, 1 and 2, were compared to their respective parent compounds in rodent models of pain. The amides significantly reduced early nociceptive and late inflammatory responses compared to nortr
