100234-59-1 Usage
General Description
1-Ethenyl-4-methoxy-9H-pyrido[3,4-b]indol-8-ol, also known as rutaecarpine, is a naturally occurring chemical compound found in the plant Evodia rutaecarpa. It is a member of the quinazolinone alkaloid family and is known for its various pharmacological properties, including anti-inflammatory, anti-tumor, and cardiovascular effects. Rutaecarpine has been studied for its potential to treat conditions such as hypertension, atherosclerosis, and cancer. It has also shown potential in regulating the metabolism of various drugs, making it a promising candidate for drug development and combination therapy. Additionally, rutaecarpine has been found to have antioxidant and hepatoprotective properties, making it a subject of interest in the field of natural medicine. Overall, 1-Ethenyl-4-methoxy-9H-pyrido[3,4-b]indol-8-ol has demonstrated a wide range of potential applications and is an intriguing compound for further research and exploration.
Check Digit Verification of cas no
The CAS Registry Mumber 100234-59-1 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,0,0,2,3 and 4 respectively; the second part has 2 digits, 5 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 100234-59:
(8*1)+(7*0)+(6*0)+(5*2)+(4*3)+(3*4)+(2*5)+(1*9)=61
61 % 10 = 1
So 100234-59-1 is a valid CAS Registry Number.
100234-59-1Relevant articles and documents
Synthetic studies on indoles and related compounds. Part 46.1 First total syntheses of 4, 8-dioxygenated β-carboline alkaloids
Suzuki, Hideharu,Unemoto, Minoru,Hagiwara, Mayumi,Ohyama, Takako,Yokoyama, Yuusaku,Murakami, Yasuoki
, p. 1717 - 1723 (2007/10/03)
Total syntheses of naturally occurring 4, 8-dioxygenated β-carboline alkaloids 2a, 2d, 2g, and 2h are described. The synthetic route involves two methodologies that we developed; (i) an improved Fischer indolization for the synthesis of a 7-oxygenated indole using a tosyl group for protection of the phenolic group, (ii) construction of a 4-methoxy-β-carboline skeleton by the C-3-selective cyclization of the C-2-substituent of the indole nucleus. The phenolic O-tosyl group of the β-carboline skeleton was successfully cleaved to the phenol by Na-anthracenide, and this phenol was methylated with TMSCH2N2.