1002352-65-9Relevant academic research and scientific papers
Synthesis of tyrosine-derived tetrahydroisoquinolines by Lewis acid catalyzed cyclization of N-(phenylsulfonyl)alkyloxazolidinones
Tussetschlaeger, Stefan,Baro, Angelika,Laschat, Sabine,Frey, Wolfgang
, p. 5590 - 5602 (2008/09/17)
N-Boc-protected tyrosine esters 5a,b were converted into tetrahydroisoquinolines 13 and 14 in four steps by reduction and ring closure to oxazolidinones 9 and 10, addition of benzenesulfinic acid and aldehydes to sulfones 11 and 12 and subsequent Lewis ac
