100239-02-9Relevant academic research and scientific papers
The Synthesis of Substituted thio>acetic Acids
Woulfe, Steven R.,Miller, Marvin J.
, p. 3133 - 3139 (2007/10/02)
The synthesis of substituted thio>acetic acids (6, thiamazins) is described.Various substituted 3(S)-(acylamino)-2-azetidinones were sulfenylated with tert-butyl (phtalimidothio)acetate.Deprotection of the tert-butyl ester with trifluoroacetic acid provided the title compounds.In sharp contrast to their oxygen analogues (oxamazins), the thiamazins were devoid of biological activity.
Electrophilic Sulfur Transfer Reactions in Organic Synthesis. Preparation of a Diastereomer of the Key Macrocyclic Component of Griseoviridin
Liu, Li,Tanke, Robin S.,Miller, Marvin J.
, p. 5332 - 5337 (2007/10/02)
The utility of electrophilic sulfur transfer reactions was demonstrated by the synthesis of a diastereomer of the key macrocyclic cycteine containing component of griseoviridin.The key step involved direct reaction at the sulfur of N-(carbobenzyloxy)-S-ph
