100239-15-4Relevant academic research and scientific papers
Insertion of Nitriles into Zirconocene 1-aza-1,3-diene Complexes: Chemoselective Synthesis of N-H and N-Substituted Pyrroles
Yu, Shasha,Xiong, Meijun,Xie, Xin,Liu, Yuanhong
supporting information, p. 11596 - 11599 (2016/02/19)
The direct insertion of nitriles into zirconocene-1-aza-1,3-diene complexes provides an efficient, chemoselective, and controllable synthesis of N-H and N-substituted pyrroles upon acidic aqueous work-up. The outcome of the reaction (that is, the formatio
Synthesis of β-lactams by condensation of the tin enolates of 2-pyridylthioesters with imines. A comparison between titanium and tin enolates
Annunziata, Rita,Benaglia, Maurizio,Cinquini, Mauro,Cozzi, Franco,Raimondi, Laura
, p. 5821 - 5828 (2007/10/02)
Addition of triethylamine to a mixture of 2-pyridylthioesters and SnCl4 or SnBr4 affords the corresponding tin(IV) enolates that add to imines to give β-lactams in fair to good yields and with various degree of trans/cis stereoselectivity. Examples of highly diastereofacially selective reactions carried out on a chiral thioester and on a chiral imine are also reported. The results are compared with those obtained in the condensations promoted by TiCl4 and TiBr4.
Studies on Lactams. Part 74. An Approach to the Total Synthesis of Amino Sugars via β-Lactams
Manhas, Maghar S.,Hedge, Vinod R.,Wagle, Dilip R.,Bose, Ajay K.
, p. 2045 - 2050 (2007/10/02)
Convenient intermediates for mono- and di-amino sugars related to antibiotics can be prepared in a stereocontrolled fashion by the rearrangement of 3,4-disubstituted azetidin-2-ones which in turn can be synthesized by stereoselective annelation of certain
