123003-79-2

Upstream product

• 124156-28-1 cis-3-isopropyl-1-(4-methoxyphenyl)-4-oxoazetidine-2-carboxylic acid 
• 546-67-8 lead(IV) tetraacetate 
• 3350-78-5 3,3-Dimethylacryloyl chloride 
• 124156-21-4 ethyl (4-methoxyphenylimino)acetate 
• 124156-34-9 1-p-anisyl-3-isopropylidene-4-carbomethoxy-2-azetidinone 
• 124175-15-1 cis-1-p-anisyl-3-(1'-methylvinyl)-4-carbomethoxy-2-azetidinone 
• 124156-25-8 cis-1-p-Methoxyphenyl-3-isopropenyl-4-ethoxycarbonylazetidinone 
• 124156-35-0 1-p-anisyl-3-isopropylidene-4-carbethoxy-2-azetidinone 
• 124156-27-0 cis-1-p-anisyl-3-isopropyl-4-carbethoxy-2-azetidinone 
• 124156-20-3 (4-methoxyphenyl-benzylidene)-carbamic acid methyl ester 
• 124156-26-9 cis-3-Isopropyl-4-(methoxycarbonyl)-1-(4-methoxyphenyl)azetidin-2-one 
• 104-94-9 4-methoxy-aniline 
• 123003-78-1 trans-4-acetyl-3-isopropyl-1-(4-methoxyphenyl)azetidin-2-one 
• 69367-52-8 methyl 2-bromo-3-methylbutanoic ester 

Downstream Products

• 82290-87-7 3-isopropyl-4-acetoxy-2-azetidinone 
• 73660-77-2 trans-4-acetoxy-3-isopropylazetidin-2-one 

Relevant academic research and scientific papers

β-Lactams via α,β-Unsaturated Acid Chlorides: Intermediates for Carbapenem Antibiotics

Stereocontrolled synthesis of α-vinyl β-lactams and their transformation to convenient intermediates for PS-5, PS-6, asparenomycin, and thienamycin are described.

The Reformatsky Type Reaction of Gilman and Speeter in the Preparation of Valuable β-Lactams in Carbapenem Synthesis: Scope and Synthetic Utility

The preparation of apppropriately substituted 3-alkyl β-lactams from the Reformatsky type reaction of Gilman and Speeter is described.Treatment of Schiff bases derived from α-methylcinnamaldehyde and amines with ethyl α-bromobutyrate or ethyl α-bromoisova