100244-26-6 Usage
Chemical structure
2-(2-deoxy-beta-D-erythro-pentofuranosyl)-6-(2,2-difluoro-2-methoxyethyl)-1,2,4-triazine-3,5(2H,4H)-dione is a complex compound consisting of a pentofuranosyl group, a difluoro-methoxyethyl group, and a triazine-dione ring.
Antiviral activity
This compound is commonly used as an antiviral drug, particularly for the treatment of HIV.
Mechanism of action
It works by inhibiting the activity of the HIV reverse transcriptase enzyme, which prevents the virus from replicating and spreading in the body.
Clinical trials
2-(2-deoxy-beta-D-erythro-pentofuranosyl)-6-(2,2-difluoro-2-methoxyethyl)-1,2,4-triazine-3,5(2H,4H)-dione has shown promising results in clinical trials, demonstrating its efficacy and low toxicity.
Therapeutic importance
Due to its effectiveness and low toxicity, this compound is considered an important therapeutic agent in the fight against HIV.
Check Digit Verification of cas no
The CAS Registry Mumber 100244-26-6 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,0,0,2,4 and 4 respectively; the second part has 2 digits, 2 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 100244-26:
(8*1)+(7*0)+(6*0)+(5*2)+(4*4)+(3*4)+(2*2)+(1*6)=56
56 % 10 = 6
So 100244-26-6 is a valid CAS Registry Number.
100244-26-6Relevant articles and documents
Synthesis and Antiviral Properties of 5-(2-Substituted vinyl)-6-aza-2'-deoxyuridines
Mitchell, William L.,Ravenscroft, Paul,Hill, Malcolm L.,Knutsen, Lars J.S.,Judkins, Brian D.,et al.
, p. 809 - 816 (2007/10/02)
The following 5-(2-substituted vinyl)-6-aza-2'-deoxyuridines were synthesized: (E)-5-(2-bromovinyl) (2) (6-aza-BVDU), 5-(2-bromo-2-fluorovinyl) (a mixture E and Z isomers) (3), (E)-5-(2-chlorovinyl) (4), (E)-5- (5), 5-(2,2-dibromoviny
