1002727-49-2Relevant articles and documents
Pyridinone diketo acids: inhibitors of HIV replication
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Page/Page column 16, (2008/06/13)
A new class of diketo acids constructed on pyridinone scaffolds, designed as inhibitors of HIV replication through inhibition of HIV integrase, is described. These compounds are useful in the prevention or treatment of infection by HIV and in the treatment of AIDS and ARC, either as the compounds, or as pharmaceutically acceptable salts, with pharmaceutically acceptable carriers, used alone or in combination with antivirals, immunomodulators, antibiotics, vaccines, and other therapeutic agents, especially other anti-HIV compounds (including other integrase-based anti-HIV agents). Methods of treating AIDS and ARC and methods of treating or preventing infection by HIV are also described.
Monocyclic heterocycles as kinase inhibitors
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Page/Page column 63, (2008/06/13)
The present invention is directed to compounds having the formula and methods for using them for the treatment of cancer.