1002796-95-3Relevant articles and documents
Design of novel N-phenylnicotinamides as selective cyclooxygenase-1 inhibitors
Shi, Lei,Li, Zi-Lin,Yang, Ying,Zhu, Zhen-Wei,Zhu, Hai-Liang
supporting information; experimental part, p. 121 - 124 (2011/02/25)
A series of N-phenylnicotinamides (1-40) were designed and evaluated in vitro for their COX inhibitory activities. Most of the synthesized compounds were proved to be potent and selective inhibitors of COX-1. Compound 28 showed the most potent COX-1 inhib