1003001-01-1

Basic information

• Product Name: ethyl 4-(5-phenyl-1H-1,2,3-triazol-1-yl)benzoate
• Synonyms: ethyl 4-(5-phenyl-1H-1,2,3-triazol-1-yl)benzoate
• CAS NO: 1003001-01-1
• Molecular Weight: 293.325
• Mol File: 1003001-01-1.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: ethyl 4-(5-phenyl-1H-1,2,3-triazol-1-yl)benzoate(CAS DataBase Reference)
• NIST Chemistry Reference: ethyl 4-(5-phenyl-1H-1,2,3-triazol-1-yl)benzoate(1003001-01-1)
• EPA Substance Registry System: ethyl 4-(5-phenyl-1H-1,2,3-triazol-1-yl)benzoate(1003001-01-1)

Safety Data

• Hazardous Substances Data: 1003001-01-1(Hazardous Substances Data)

Upstream product

• 38556-93-3 4-azido-benzoic acid ethyl ester 
• 16222-10-9 1-phenyl-2-(phenylthio)ethanone 
• 94-09-7 p-aminoethylbenzoate 
• 536-74-3 phenylacetylene 

Relevant articles and documents

An Organocatalytic Regiospecific Synthesis of 1,5-Disubstituted 4-Thio-1,2,3-triazoles and 1,5-Disubstituted 1,2,3-Triazoles

Organocatalytic azide-ketone [3+2] cycloaddition (OrgAKC) of a variety of 1-aryl-2-(arylthio)ethanones and 1-alkyl-2-(alkylthio)ethanones with different aryl or alkyl azides is reported in dimethyl sulfoxide or solvent-free under ambient conditions to furnish 1,5-disubstituted 4-thio-1,2,3-triazoles in a regiospecific manner, which are further converted into useful 1,5-disubstituted 1,2,3-triazoles by treatment with Raney Ni at 25 ?C for 1-3 h. Notable features of the OrgAKC reaction include high rate and selectivity, solvent-free conditions, easily available substrates and catalysts, a wide range of synthetic and medicinal applications, and excellent yields generating a vast library of triazoles.

Ruthenium-catalyzed cycloaddition of aryl azides and alkynes

The formation of 1,5-disubstituted 1,2,3-triazoles from aryl azides and alkynes was readily accomplished using [Cp*RuCl]4 catalyst in dimethylformamide. It was also demonstrated that the reaction provided higher yields, cleaner product, and sho