1003034-67-0Relevant academic research and scientific papers
Synthesis of substituted 2-phenylhistamines via a microwave promoted Suzuki coupling
Skoumbourdis, Amanda P.,Moore, Susanna,Landsman, Marc,Thomas, Craig J.
, p. 9140 - 9143 (2008/09/17)
Substitutions on the 2-position of the imidazole ring of histamine have proven useful in a number of biochemical settings. Current art for the synthesis of these constructs relies upon a cumbersome and low-yielding condensation reaction. Here-in we report a new procedure for the synthesis of a series of substituted 2-phenylhistamines utilizing a microwave-promoted Suzuki coupling.
