100318-30-7 Usage
Description
C12H17N3OS, also known as 2-[(4-Butoxyphenyl)methylene]hydrazinecarbothioamide, is an organic compound with potential applications in various fields. It is characterized by its molecular structure that includes a butoxyphenyl group, a hydrazinecarbothioamide group, and a sulfur atom. This unique structure endows it with specific properties that make it suitable for use in different industries.
Uses
Used in Pharmaceutical Industry:
C12H17N3OS is used as a precursor in the synthesis of 4-O-substituted phenylmethylenethiosemcarbazones, which are known to exhibit tyrosinase inhibitory properties. Tyrosinase is a key enzyme involved in the melanin synthesis process, and its inhibition can be beneficial in treating hyperpigmentation and other skin conditions. The development of these compounds can lead to the creation of new drugs and treatments for various skin-related disorders.
Used in Cosmetics Industry:
In the cosmetics industry, C12H17N3OS and its derivatives can be used as active ingredients in skin care products. Their tyrosinase inhibitory properties can help reduce the appearance of dark spots, age spots, and other pigmentation issues, providing a more even and radiant skin tone.
Used in Research and Development:
C12H17N3OS can also be utilized in research and development for the discovery of new compounds with potential therapeutic applications. Its unique structure and properties make it an interesting candidate for further exploration in the fields of medicinal chemistry and drug design.
Check Digit Verification of cas no
The CAS Registry Mumber 100318-30-7 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,0,0,3,1 and 8 respectively; the second part has 2 digits, 3 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 100318-30:
(8*1)+(7*0)+(6*0)+(5*3)+(4*1)+(3*8)+(2*3)+(1*0)=57
57 % 10 = 7
So 100318-30-7 is a valid CAS Registry Number.
100318-30-7Relevant articles and documents
Rational design and synthesis of 4-O-substituted phenylmethylenethiosemicarbazones as novel tyrosinase inhibitors
Yi, Wei,Cao, Rihui,Chen, Zhiyong,Yu, Liang,Wen, Huan,Yan, Qin,Ma, Lin,Song, Huacan
experimental part, p. 752 - 754 (2010/07/15)
In continuing our program aimed to search for tyrosinase inhibitors, a series of novel 4-O-substituted phenylmethylenethiosemicarbazones were rational designed, synthesized and their inhibitory effects on the diphenolase activity of mushroom tyrosinase were also evaluated. A fair number of compounds were found to have significant tyrosinase inhibitiory activity. Particularly, the IC50 values of compounds 3a-g, 3j and 3s were of the same magnitude as tropolone, one of the best tyrosinase inhibitors known so far. Furthermore, the structure-activity relationships of these compounds were also investigated. All these data suggested that these molecules might be utilized for the development of new candidate for the treatment of dermatological disorders, and further development of such compounds may be of interest.
