1003318-67-9

Usage

Uses

1. Used in Pharmaceutical Industry:
1-(4-[4-[(5RS)-5-(2,6-difluorophenyl)-4,5-dihydro-1,2-oxazol-3-yl]-1,3-thiazole-2-yl]-1-piperidinyl)-2-[5-methyl-3-(trifluoromethyl)-1H-pyrazol-1-yl]ethanone is used as a pharmaceutical compound for its potential therapeutic applications. Its unique chemical structure allows it to interact with specific biological targets, making it a promising candidate for the development of new drugs.
2. Used in Chemical Research:
1-(4-[4-[(5RS)-5-(2,6-difluorophenyl)-4,5-dihydro-1,2-oxazol-3-yl]-1,3-thiazole-2-yl]-1-piperidinyl)-2-[5-methyl-3-(trifluoromethyl)-1H-pyrazol-1-yl]ethanone is also utilized in chemical research for understanding its properties, reactivity, and potential applications in various chemical processes. Its unique structure and properties make it an interesting subject for further investigation and development.
3. Used in Environmental Studies:
Due to its stable hydrolysis and degradation properties, 1-(4-[4-[(5RS)-5-(2,6-difluorophenyl)-4,5-dihydro-1,2-oxazol-3-yl]-1,3-thiazole-2-yl]-1-piperidinyl)-2-[5-methyl-3-(trifluoromethyl)-1H-pyrazol-1-yl]ethanone can be used in environmental studies to assess its impact on ecosystems and to develop strategies for its safe use and disposal.
4. Used in Material Science:
The compound's physical properties, such as its melting point and vapor pressure, make it a candidate for use in material science research, where it could potentially be incorporated into the development of new materials with specific properties and applications.

Pharmacology

Oxathiapiprolin is the first member of a new class of highly active oomycete fungicides, the piperidinyl thiazole isoxazolines. It is effective at extremely low use rates and shows excellent preventative and curative efficacy, excellent antisporulant properties, and long residual control with protection of new growth. It was discovered using a high-throughput screening approach with diverse structural classes and optimized to this high potency chemotype by conformationally restricting the benzyl amide moiety using an isoxazoline ring as an amide bioisostere. Oxathiapiprolin has a novel site of action, binding strongly to an OSBP with an, as yet, unknown cellular function. Oxathiapiprolin has the perfect combination of attributes to provide outstanding oomycete disease control and is being developed globally as DuPont? Zorvec? disease control. We expect that products containing oxathiapiprolin will become valuable tools for growers in their efforts to combat these diseases and sustainably and responsibly meet the growing global food production needs.

Upstream product

• 1003319-95-6 1-[2-(5-methyl-3-trifluoromethyl-pyrazol-1-yl)-acetyl]-piperidine-4-carbothioic acid amide 
• 1253189-14-8 2-chloro-1-[5-(2,6-difluorophenyl)-4,5-dihydroisoxazol-3-yl]ethanone 
• 1173693-37-2 2-bromo-1-(4,5-dihydro-5-(2,6-difluorophenyl)-3-isoxazolyl)ethanone 

Relevant academic research and scientific papers

FUNGICIDAL MIXTURES

Disclosed is a fungicidal composition comprising (a) at least one compound selected from the compounds of Formula 1 N-oxides, and salts thereof, wherein R1, R2, A, G, W, Z1, X, J, and n are as defined in the disclosure, and (b) at least one additional fungicidal compound. Also disclosed is a method for controlling plant diseases caused by fungal plant pathogens comprising applying to the plant or portion thereof, or to the plant seed, a fungicidally effective amount of the aforesaid composition. Also disclosed is a composition comprising component (a) of aforesaid composition and at least one insecticide. Also disclosed are compounds of Formula 1A, 1B and 1C, wherein R1, R2, A, G, W, Z1, X, J, n, Z3, M and J1 are as defined in the disclosure.

SOLID FORMS OF AN AZOCYCLIC AMIDE

Disclosed are solid forms of 1-[4-[4-[5-(2,6-difluorophenyl)-4,5-dihydro-3-isoxazolyl]-2-thiazolyl]-1-piperidinyl]-2-[5-methyl-3-(trifluoromethyl)-1H-pyrazol-1-yl]ethanon e (Compound 1). Methods for the preparation of solid forms of Compound 1 and for the