1003322-53-9Relevant articles and documents
PYRIDAZINONE COMPOUNDS
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Page/Page column 62, (2008/12/07)
The invention is directed to pyridazinone compounds and pharmaceutical compositions containing such compounds that are useful in treating infections by hepatitis C virus.
Synthesis of new pyridazinone derivatives: 2,6-Disubstituted 5-hydroxy-3(2H)-pyridazinone-4-carboxylic acid ethyl esters
Li, Lian-Sheng,Zhou, Yuefen,Zhao, Jingjing,Dragovich, Peter S.,Stankovic, Nebojsa,Bertolini, Thomas M.,Murphy, Douglas E.,Sun, Zhongxiang,Tran, Chinh V.,Ayida, Benjamin K.,Ruebsam, Frank,Webber, Stephen E.
, p. 3301 - 3308 (2008/09/20)
2,6-Disubstituted 5-hydroxy-3(2H)-pyridazinone-4-carboxylic acid ethyl esters were synthesized from α-keto esters via an efficient three-step sequence including hydrazone formation, acylation with ethyl malonyl chloride, and subsequent Dieckmann cyclizati