1003379-16-5Relevant academic research and scientific papers
Affinity-based labeling of cytohesins with a bifunctional SecinH3 photoaffinity probe
Bi, Xihe,Schmitz, Anton,Hayallah, Alaa M.,Song, Jin-Na,Famulok, Michael
scheme or table, p. 9565 - 9568 (2009/05/06)
(Chemical Equation Presented) The specific binding of the cytohesin inhibitor SecinH3 to Sec7 domains of cytohesins was shown by the use of a bifunctional photoaffinity probe (see structure) on guanine nucleotide exchange factors (GEFs) and GTPases. This probe should be useful for the proteome-wide profiling of cytohesin complexes and the identification of the binding site.
