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1003751-09-4

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1003751-09-4 Usage

General Description

1-(2,4-DiMethylphenyl)-3-phenyl-1H-pyrazol-5(4H)-one, also known as ketoprofen, is a nonsteroidal anti-inflammatory drug (NSAID) that is used to treat pain and inflammation. It works by inhibiting the production of prostaglandins, which are substances in the body that cause pain and inflammation. Ketoprofen is commonly used to treat conditions such as arthritis, menstrual cramps, muscle aches, and dental pain. It is available in various forms including oral tablets, capsules, and topical creams, and is usually taken as needed for pain relief. However, it should be used with caution as it may have potential side effects such as stomach ulcers, bleeding, and kidney problems. Overall, ketoprofen is an effective medication for managing pain and inflammation, but should be used under the guidance of a healthcare professional.

Check Digit Verification of cas no

The CAS Registry Mumber 1003751-09-4 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,0,0,3,7,5 and 1 respectively; the second part has 2 digits, 0 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 1003751-09:
(9*1)+(8*0)+(7*0)+(6*3)+(5*7)+(4*5)+(3*1)+(2*0)+(1*9)=94
94 % 10 = 4
So 1003751-09-4 is a valid CAS Registry Number.

1003751-09-4Downstream Products

1003751-09-4Relevant articles and documents

Asymmetric [3 + 3] Annulation of Copper-Allenylidenes with Pyrazolones: Synthesis of Chiral 1,4-Dihydropyrano[2,3- c]pyrazoles

Jiang, Feng,Feng, Xinping,Wang, Rou,Gao, Xing,Jia, Hao,Xiao, Yumei,Zhang, Cheng,Guo, Hongchao

supporting information, p. 5278 - 5281 (2018/09/13)

The copper-catalyzed asymmetric [3 + 3] annulation of ethynyl benzoxazinanones with pyrazolones has been achieved, providing simple access to 1,4-dihydropyrano[2,3-c]pyrazole derivatives in moderate to excellent yields with excellent enantioselectivities (up to 99% ee). Compared with previous annulation reactions of copper-allenylidenes from ethynyl benzoxazinanones, the current reaction fused the three carbon atoms of the propargyl moiety into a heterocyclic framework.

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