100383-13-9

Usage

InChI:InChI=1/C7H8N4O/c1-12-7-10-5(8)4-2-3-9-6(4)11-7/h2-3H,1H3,(H3,8,9,10,11)

Upstream product

• 74895-37-7 2-Cyan-4,4-diethoxybuttersaeurenitril 
• 29427-58-5 O-methylisourea hemisulfate 
• 96022-83-2 4-amino-7-(2'-deoxy-β-D-erythro-pentofuranosyl)-2-methoxy-7H-pyrrolo<2,3-d>pyrimidine 

Downstream Products

• 698376-41-9 2-methoxy-7-(3,5-di-O-toluoyl-2-deoxy-β-D-ribofuranosyl)-pyrrolo[2,3-d]pyrimidin-4-ylamine 
• 698376-58-8 4-amino-7-(3,5-di-O-toluoyl-2-deoxy-β-D-ribofuranosyl)-pyrrolo[2,3-d]pyrimidin-2(3H)-one 
• 100047-45-8 4-amino-1,7-dihydro-2H-pyrrolo<2,3-d>pyrimidin-4-one 

Relevant academic research and scientific papers

Non-standard nucleobases implementing the isocytidine and isoguanosine hydrogen bonding patterns

This invention provides compositions of matter that, when incorporated into an oligonucleotide, present to a complementary strand in a Watson-Crick pairing geometry a pattern of hydrogen bonds that is different from the pattern presented by adenine, guani

Furanoside-Pyranoside Isomerization of Tubercidin and its 2'-Deoxy Derivatives: Influence of Nucleobase and Sugar Structure on the Proton-catalysed Reaction

2'-Deoxy-2-methoxytubercidin (6a) which was prepared from the nucleobase (1a) with the halogenose (2) via phase-transfer glycosylation isomerizes rapidly under acidic conditions.Two pyranosides and the anomeric furanoside (5a) are formed.The isomerization process was followed kinetically, demonstrating that furanoside formation is kinetically controlled whereas the β-pyranoside (7a) is the thermodynamically most stable product.From 2'-deoxytubercidin (6b) similar results were obtained but isomerization was slow, compared with (6a).The ribonucleoside tubercidin (6c) did isomerize only under vigorous acid treatment leading to the α-furanoside (5c) and the nucleobase (1c) by cleavage of the N-glycosylic bond.