1003852-48-9

Basic information

• Product Name: C₂₁H₃₀ClFN₂O₂
• CAS NO: 1003852-48-9
• Molecular Weight: 396.933
• Mol File: 1003852-48-9.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: C₂₁H₃₀ClFN₂O₂(CAS DataBase Reference)
• NIST Chemistry Reference: C₂₁H₃₀ClFN₂O₂(1003852-48-9)
• EPA Substance Registry System: C₂₁H₃₀ClFN₂O₂(1003852-48-9)

Safety Data

• Hazardous Substances Data: 1003852-48-9(Hazardous Substances Data)

Upstream product

• 93081-15-3 O-(2-chloro-6-fluoro-benzyl)-hydroxylamine hydrochloride 

Relevant articles and documents

Synthesis and fungicidal activity of macrolactams and macrolactones with an oxime ether side chain

Three series of novel macrolactams and macrolactones - 12-alkoxyimino- tetradecanlactam, 12-alkoxyiminopentadecanlactam, and 12-alkoxyiminodecanlactone derivatives (7A, 7B, and 7C) - were synthesized from corresponding 12-oxomacrolactams and 12-oxomacrolactone. Their structures were confirmed by 1H NMR and elemental analysis. The Z and E isomers of 7A and 7B were separated, and their configurations were determined by 1H NMR. These compounds showed fair to excellent fungicidal activities against Rhizoctonia solani Kuehn. It is interesting that the Z and E isomers of most of the compounds have quite different fungicidal activities. The fact that the compounds have a gradual increase of fungicidal activity in the order of 7A, 7C, and 7B indicated that the macrocyclic derivatives with a hydrogen-bonding acceptor (=N-O-) and a hydrogen-bonding donor (-CONH-) on the ring, and a three methylenes distance (CH2CH2CH2) between these two functional groups, exhibited the best fungicidal activity. The bioassay also showed that 7B not only has good fungicidal activity but also may have a broad spectrum of fungicidal activities.