100393-88-2Relevant academic research and scientific papers
Synthesis and cyclization reaction of pyrazolin-5-one derivatives
Jung, Jae-Chul,Blake Watkins,Avery, Mitchell A.
, p. 77 - 94 (2005)
A versatile synthetic method for preparing 3-pyrazolin-5-ones and 5,8-dihydro-1H-pyrazolo[1,2-a]pyridazines from simple β-keto esters is demonstrated. The synthetic strategies involve the acylation of β-keto esters, cyclocondensation with hydrazine followed by trapping with a diene under oxidative conditions.
