100414-80-0 Usage
General Description
Dan shen spiroketal lactone, also known as tanshinone IIA, is a chemical compound extracted from the root of the plant Salvia miltiorrhiza, commonly known as red sage or dan shen. It has been used in traditional Chinese medicine for centuries for its cardiovascular and neuroprotective effects. Tanshinone IIA has been studied for its anti-inflammatory, antioxidant, and anti-cancer properties. It has also been shown to have potential therapeutic effects in treating cardiovascular diseases, diabetes, and neurodegenerative disorders. Tanshinone IIA is a promising natural compound with various pharmacological activities that make it a subject of increasing interest in scientific research and drug development.
Check Digit Verification of cas no
The CAS Registry Mumber 100414-80-0 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,0,0,4,1 and 4 respectively; the second part has 2 digits, 8 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 100414-80:
(8*1)+(7*0)+(6*0)+(5*4)+(4*1)+(3*4)+(2*8)+(1*0)=60
60 % 10 = 0
So 100414-80-0 is a valid CAS Registry Number.
InChI:InChI=1/C17H16O3/c1-10-8-17(19-9-10)14-7-6-12-11(2)4-3-5-13(12)15(14)16(18)20-17/h3-7,10H,8-9H2,1-2H3/t10-,17?/m1/s1
100414-80-0Relevant articles and documents
Total synthesis of danshenspiroketallactone
Chorley, Daniel F.,Chen, Jack Li-Yang,Furkert, Daniel P.,Sperry, Jonathan,Brimble, Margaret A.
, p. 128 - 130 (2012/02/03)
Described herein is the first synthesis of the monobenz-annulated 5,5-spiroketals danshenspiroketallactone and epi-danshen-spiroketallactone, two components of the traditional Chinese medicine Danshen. Key features of the synthesis include a directed metallation-lactonisation sequence to install the isobenzofuranone moiety and an oxidative radical cyclisation to afford the monobenz-annulated 5,5-spiroketal. Georg Thieme Verlag Stuttgart. New York.
