100422-85-3

Upstream product

• 17903-41-2 phenyl(trimethylsilyl)methyl bromide 
• 1074-82-4 potassium phtalimide 

Downstream Products

• 100422-94-4 erythro-1-(2-furyl)-2-phenyl-2-phthalimidoethanol 
• 100422-94-4 threo-1-(2-furyl)-2-phenyl-2-phthalimidoethanol 
• 100422-96-6 erythro-(E)-1,4-diphenyl-1-phthalimido-3-buten-2-ol 
• 100422-96-6 threo-(E)-1,4-diphenyl-1-phthalimido-3-buten-2-ol 
• 100422-90-0 erythro-1-(p-methylphenyl)-2-phenyl-2-phthalimidoethanol 
• 100422-90-0 threo-1-(p-methylphenyl)-2-phenyl-2-phthalimidoethanol 
• 100422-88-6 erythro-1,2-diphenyl-2-phthalimidoethanol 
• 100422-88-6 threo-1,2-diphenyl-2-phthalimidoethanol 
• 100422-92-2 erythro-1-(p-methoxyphenyl)-2-phenyl-2-phthalimidoethanol 
• 100422-92-2 threo-1-(p-methoxyphenyl)-2-phenyl-2-phthalimidoethanol 
• 2142-01-0 N-benzylphthalimide 
• 100422-98-8 erythro-1-phenyl-1-phthalimido-2-pentanol 
• 100422-98-8 threo-1-phenyl-1-phthalimido-2-pentanol 
• 100423-11-8 α-(trimethylsilyl)benzylamine 

Relevant academic research and scientific papers

Nucleophilic Aminomethylation of Aldehydes with α-Amino Alkylsilanes

Fluoride-induced desilylation of (α-phthalimido-, α-morpholino-, and α-acetamidobenzyl)silanes and a (phthalimidomethyl)silane generates the corresponding α-amino carbanions which add to a variety of aldehydes.The conversion of phthalimido group of the adducts into amino moiety leads to β-amino alcohols.This simple reaction sequence offers a new and general method of nucleophilic aminomethylation.