100440-64-0

Upstream product

• 67-56-1 methanol 
• 100440-57-1 1-benzyl-2-thiobenzimidazole-5-carboxylic acid 
• 68502-46-5 4-benzylamine-3-nitro-benzoic acid methyl ester 
• 68502-22-7 3-amino-4-benzylamine-benzoic acid methyl ester 
• 214903-69-2 1-Benzyl-2-oxo-2,3-dihydro-1H-benzoimidazole-5-carboxylic acid methyl ester 

Downstream Products

• 214903-72-7 1-Benzyl-2-(4-methyl-piperazin-1-yl)-1H-benzoimidazole-5-carboxylic acid methyl ester 
• 214903-73-8 1-Benzyl-2-(4-methyl-piperidin-1-yl)-1H-benzoimidazole-5-carboxylic acid methyl ester 
• 214903-78-3 1-Benzyl-2-(4-methyl-piperazin-1-yl)-1H-benzoimidazole-5-carboxylic acid 
• 214903-75-0 1-Benzyl-2-(4-methyl-piperidin-1-yl)-1H-benzoimidazole-5-carboxylic acid 

Relevant academic research and scientific papers

Synthesis of some new benzimidazolecarboxamides and evaluation of their antimicrobial activity

A series of 1,2-disubstituted benzimidazole-5(6)-carboxamides was prepared and evaluated in vitro for antimicrobial activity against Staphyloccus aureus, Escherichia coli and Candida albicans. The precursor benzimidazolecarboxylic acids 4a-c and 9a-c were

REACTION OF 2-THIOBENZAZOLES WITH THIONYL CHLORIDE

A new reaction in the benzimidazole series, viz., replacement of the mercapto group by chlorine by the action of thionyl chloride on 2-thiobenzimidazoles, was discovered.Benzoxazolone is formed by treatment of 2-thiobenzoxazole with thionyl chloride, and 2,2'-dithiobis(2-benzothiazole) is formed from 2-thiobenzothiazole.