1004520-53-9Relevant academic research and scientific papers
Mild and efficient one-pot synthesis of chiral β-chalcogen amides via 2-oxazoline ring-opening reaction mediated by indium metal
Braga, Antonio L.,Galetto, Fábio Z.,Taube, Paulo S.,Paix?o, Márcio W.,Silveira, Claudio C,Singh, Devender,Vargas, Fabrício
scheme or table, p. 3563 - 3566 (2009/02/07)
A simple and efficient procedure for the synthesis of β-seleno and β-thio amides via the ring-opening reaction of chiral 2-oxazolines in the presence of indium metal has been developed. Features of this method include the following: (i) easily and accessi
Modular chiral β-selenium-, sulfur-, and tellurium amides: synthesis and application in the palladium-catalyzed asymmetric allylic alkylation
Vargas, Fabrício,Sehnem, Jasquer A.,Galetto, Fabio Z.,Braga, Antonio L.
, p. 392 - 398 (2008/04/01)
A series of modular chiral β-chalcogen amides have been efficiently synthesized from inexpensive and easily available 2-oxazolines. All the selenium, sulfur, and tellurium compounds were evaluated as chiral ligands in the palladium-catalyzed asymmetric al
Chiral β-amino sulfoxides. Synthesis, configurational assignment and conformational analysis based on X-ray, CD, 1H NMR and theoretical calculations
Lewanowicz,Lipinski,Siedlecka,Skarzewski,Baert
, p. 6571 - 6586 (2007/10/03)
Enantiomerically pure u and l β-amino sulfoxides have been easily obtained from the respective homochiral α-amino alcohols. The absolute configuration at the created stereogenic centre was assigned by CD spectra and by X-ray analysis. Conformational analysis of the title compounds was carried out using quantum chemical energy-geometry optimization. Thus established conformational behavior explained the strongly configuration dependent NMR spectral patterns observed for the u and l diastereomers.
