1004538-33-3

Usage

Uses

Used in Pharmaceutical Industry:
(R)-1-BOC-3-DIMETHYLAMINOPYRROLIDINE is used as a chiral base in organic synthesis for its ability to form chiral centers in molecules, which is crucial for the development of enantiomerically pure pharmaceutical compounds. The presence of its tertiary amine makes it a suitable candidate for the synthesis of various complex organic compounds, contributing to the advancement of drug discovery and development.
Used in Chemical Synthesis:
(R)-1-BOC-3-DIMETHYLAMINOPYRROLIDINE is used as a key intermediate in the synthesis of various organic compounds, including pharmaceuticals, agrochemicals, and other specialty chemicals. Its chiral properties and tertiary amine functionality enable the formation of diverse molecular structures, making it a versatile building block in chemical synthesis.
Used in Research and Development:
R-DMAP is utilized as a research tool in the study of asymmetric synthesis, chiral recognition, and enantioselective reactions. Its unique properties allow chemists to explore new methods and techniques for the synthesis of chiral compounds, leading to the discovery of novel pharmaceuticals and other chiral products with potential applications in various industries.

Upstream product

• 1004538-32-2 (R)-1-(tert-butoxycarbonyl)-3-dimethylaminopyrrolidine hydrochloric acid salt 
• 50-00-0 formaldehyd 
• 147081-49-0 (R)-3-aminopyrrolidine-1-carboxylic acid tert-butyl ester 

Downstream Products

• 1359969-37-1 2-chloro-4-(3-cyclopentyl-7-((R)-3-(N,N-dimethylamino)pyrrolidine-1-carbonyl)-3,3a,4,5-tetrahydro-2H-pyrazolo[3,4-f]quinolin-2-yl)benzonitrile 

Relevant academic research and scientific papers

FUSED RING COMPOUND FOR USE AS MINERALOCORTICOID RECEPTOR ANTAGONIST

The present invention belongs to the technical field of medicine, relating in particular to: a fused ring compound as represented by Formula (I) for use as a mineralocorticoid receptor antagonist, a pharmaceutically acceptable salt thereof, and an isomer thereof; a preparation method for these compounds; a pharmaceutical preparation containing these compounds; and an application of these compounds, the pharmaceutically acceptable salt thereof, or the isomers thereof in the preparation of medicants for the treatment and/or prevention of kidney injury, cardiovascular diseases such as hypertension, and/or endocrine disease. The definitions of X, Y1, Y2, Y3, R1, R2a,R2b , R3a , R3b, R4, Cy and n are as presented in the description.

METHOD FOR PRODUCTION OF OPTICALLY ACTIVE 3-AMINO-NITROGENATED COMPOUND

Aiming at production of an optically active 3-amino nitrogen-containing compound which is useful as an intermediate in synthesis of medicines and pesticides, in particular, an optically active 1-protected-3-aminopyrrolidine derivative, from an inexpensive and readily available raw material by a process which is efficient and can be practiced industrially, an optically active 3-amino nitrogen-containing compound is produced by performing a reaction of an optically active 3-substituted nitrogen-containing compound with ammonia, methylamine, ethylamine or dimethylamine in the presence of water. In addition, a 1-protected-3-aminopyrrolidine derivative is produced by performing a reaction of an optically active 1-protected-3-(sulfonyloxy)pyrrolidine derivative with ammonia, methylamine, ethylamine, or dimethylamine in the presence of methanol, ethanol, n-propanol, or isopropanol under a pressure of less than 30 barr.