100462-43-9 Usage
Uses
Used in Organic Synthesis:
Succinic acid-mono-N-phenylsulfonylamide is used as a reagent for the preparation of pharmaceuticals and biologically active molecules, leveraging its ability to facilitate the formation of amide bonds in chemical reactions.
Used in Catalyst Applications:
In the field of chemical reactions, succinic acid-mono-N-phenylsulfonylamide serves as a catalyst to enhance the rate of specific reactions, particularly those involving the formation of amide bonds, thus improving the efficiency of organic synthesis processes.
Used in Pharmaceutical Development:
SUCCINIC ACID-MONO-N-PHENYLSULFONYLAMIDE is utilized in the development of new pharmaceuticals, given its potential to contribute to the synthesis of medicinally relevant molecules, thereby expanding the scope of available treatments.
Used in Antimicrobial and Antiparasitic Research:
Succinic acid-mono-N-phenylsulfonylamide is explored for its potential antimicrobial and antiparasitic properties, indicating its use in the research and development of new agents to combat infectious diseases.
Used in Chemical Reactions:
In the chemical industry, succinic acid-mono-N-phenylsulfonylamide is used as a catalyst to accelerate specific chemical reactions, which is crucial for the production of various chemical products and intermediates.
Check Digit Verification of cas no
The CAS Registry Mumber 100462-43-9 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,0,0,4,6 and 2 respectively; the second part has 2 digits, 4 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 100462-43:
(8*1)+(7*0)+(6*0)+(5*4)+(4*6)+(3*2)+(2*4)+(1*3)=69
69 % 10 = 9
So 100462-43-9 is a valid CAS Registry Number.
InChI:InChI=1/C10H11NO5S/c12-9(6-7-10(13)14)11-17(15,16)8-4-2-1-3-5-8/h1-5H,6-7H2,(H,11,12)(H,13,14)
100462-43-9Relevant academic research and scientific papers
Chong, MuiPhin,Toh, LeeRoy,Tumber, Anthony,Chan, YanYing,Chan, MunChiang,Abboud, Martine I.,Schofield, Christopher J.,Yeoh, KarKheng
, p. 977 - 986 (2021)
There is current interest in developing human hypoxia-inducible factor (HIF) prolyl hydroxylase domain (PHD) inhibitors for the treatment of anemia and other hypoxia-related diseases. We describe the synthesis of 3-carbamoylpropanoic acid derivatives and their evaluation as human PHD-2 inhibitors. MS assays indicated that derivatives with a 3-carbamoylpropanoic acids-containing benzoxazole moiety are inhibitors of PHD-2 with IC50 values of 2.24 μM and 1.32 μM, respectively. However, neither the acids nor their respective ethyl esters were observed to upregulate HIF-1α levels in cells.
