100491-52-9 Usage
Molecular structure
1,8-Naphthyridine-3-carboxylic acid, 6-fluoro-1-(4-fluorophenyl)-1,4-dihydro-7-(4-methyl-1-piperazinyl)-4-oxo, ethyl ester is a heterocyclic compound with various functional groups, including fluoro, piperazinyl, and ethyl ester groups.
Biological activity
1,8-Naphthyridine-3-carboxylic acid,
6-fluoro-1-(4-fluorophenyl)-1,4-dihydro-7-(4-methyl-1-piperazinyl)-4-oxo-
, ethyl ester has potential pharmaceutical applications due to its various biological activities, which are not yet fully understood.
Fluoro and piperazinyl groups
The presence of these groups makes the compound potentially useful in drug development, particularly in the field of antimicrobial and antiviral agents.
Ethyl ester derivative
The compound is an ethyl ester derivative of 1,8-Naphthyridine-3-carboxylic acid, which may affect its pharmacokinetic and pharmacodynamic properties.
Further research needed
More research and testing are required to evaluate the full potential of 1,8-Naphthyridine-3-carboxylic acid,
6-fluoro-1-(4-fluorophenyl)-1,4-dihydro-7-(4-methyl-1-piperazinyl)-4-oxo-
, ethyl ester and determine its pharmacological profile. This includes understanding its mechanism of action, efficacy, safety, and potential side effects.
Check Digit Verification of cas no
The CAS Registry Mumber 100491-52-9 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,0,0,4,9 and 1 respectively; the second part has 2 digits, 5 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 100491-52:
(8*1)+(7*0)+(6*0)+(5*4)+(4*9)+(3*1)+(2*5)+(1*2)=79
79 % 10 = 9
So 100491-52-9 is a valid CAS Registry Number.
100491-52-9Relevant academic research and scientific papers
Synthesis and Structure-Activity Relationships of New Arylfluoronaphthyridine Antibacterial Agents
Chu, Daniel T. W.,Fernandes, Prabhavathi B.,Claiborne, Akiyo K.,Gracey, Eugene H.,Pernet, Andre G.
, p. 2364 - 2369 (2007/10/02)
Novel arylfluoro-1,4-dihydro-4-oxo-1,8-naphthyridine-3-carboxylic acid have been prepared and their antibacterial activity evaluated.These derivatives are characterized by having a fluorine atom at 6-position, substituted amino groups at the 7-position, and substituted phenyl groups at the 1-position.The in vitro antibacterial potency is greatest when the 1-substituent is either p-fluorophenyl or o,p-difluorophenyl and the 7-substituent is a 3-amino-1-pyrrolidinyl group. 1-(2,4-Difluorophenyl)-6-fluoro-7-(3-amino-1-pyrrolidinyl)-1,4-dihydro-4-oxo-1,8-naphthyridine-3-carboxylic acid (38) was found to possess excellent in vitro potency and in vivo efficacy.
