1004981-25-2Relevant academic research and scientific papers
Michael addition-elimination reactions of chiral enolates with ethyl 3-halopropenoates
Esteban, Jorge,Costa, Anna M.,Gomez, Alex,Vilarrasa, Jaume
, p. 65 - 68 (2008/09/18)
Key dienoic or dienal substructures of cytotoxic macrolides amphidinolide E and dictyostatin have been prepared via a Michael addition (followed by elimination of X-) of chiral enolates on β-halo derivatives of ethyl acrylate, with full retention of the i
