31930-36-6

Basic information

• Product Name: CIS-3-IODOACRYLIC ACID ETHYL ESTER
• Synonyms: CIS-3-IODOACRYLIC ACID ETHYL ESTER;ETHYL CIS-3-IODOACRYLATE;Ethyl cis-3-Iodoacrylate (stabilized with Copper chip);(Z)-ethyl 3-iodoacrylate;Ethyl cis-3-iodoacrylate 98%;Ethyl cis-3-Iodoacrylate Ethyl cis-3-Iodoacrylate (stabilized with Copper chip)
• CAS NO: 31930-36-6
• Molecular Formula: C₅H₇IO₂
• Molecular Weight: 226.01
• Product Categories: C2 to C5;Carbonyl Compounds;Esters;Building Blocks;C2 to C5;Carbonyl Compounds;Chemical Synthesis;Organic Building Blocks
• Mol File: 31930-36-6.mol
• Article Data: 37

Chemical Properties

• Boiling Point: 85 °C20 mm Hg(lit.)
• Flash Point: 210 °F
• Appearance: /
• Density: 1.765 g/mL at 25 °C(lit.)
• Vapor Pressure: 0.359mmHg at 25°C
• Refractive Index: n20/D 1.533(lit.)
• Storage Temp.: Refrigerator
• Solubility: Chloroform, Ethyl Acetate (Slightly)
• CAS DataBase Reference: CIS-3-IODOACRYLIC ACID ETHYL ESTER(CAS DataBase Reference)
• NIST Chemistry Reference: CIS-3-IODOACRYLIC ACID ETHYL ESTER(31930-36-6)
• EPA Substance Registry System: CIS-3-IODOACRYLIC ACID ETHYL ESTER(31930-36-6)

Safety Data

• Hazard Codes: Xi
• Statements: 36/37/38
• Safety Statements: 26
• WGK Germany: 3
• Hazardous Substances Data: 31930-36-6(Hazardous Substances Data)

Usage

Uses

Different sources of media describe the Uses of 31930-36-6 differently. You can refer to the following data:
1. Ethyl Cis-?3-?iodoacrylate is a reactant used in the synthesis of complex naphtho(benzo)furans as well as in the cobalt-catayzed cross coupling of functionalized organozinc pivalates.
2. Ethyl cis-3-iodoacrylate may be used in the synthesis of the following:vinyl sulfides(Z)-1-iodohept-1-en-3-ol(E)-1-iodohept-1-en-3-ol(Z)-β-iodoacrolein6-oxo-M1Guo

General Description

Ethyl cis-3-iodoacrylate (cis-ethyl-β-iodoacrylate, ethyl (Z)-β-iodoacrylate) is Z-vinyl iodide derivative. It is reported to be prepared from ethyl propiolate by treating with sodium iodide. Its Suzuki coupling reaction with cyclic vinyl boronic acids has been studied.

InChI:InChI=1/C5H7IO2/c1-2-8-5(7)3-4-6/h3-4H,2H2,1H3/b4-3-

Upstream product

• 623-47-2 propynoic acid ethyl ester 
• 16205-84-8 ethyl 3-(trimethylsilyl)propynoate 
• 64-17-5 ethanol 
• 6214-35-3 (Z)-3-iodoprop-2-enoic acid 
• 6372-02-7 (E)-3-iodoacrylic acid 
• 71815-44-6 (E/Z)-3-iodoacrylic acid 

Downstream Products

• 133218-12-9 ethyl (E)-6-(4-methoxyphenyl)-4-hexyn-2-enoate 
• 39806-23-0 ethyl (2E,4E,6E)-7-phenyl-2,4,6-heptatrienoate 
• 2048-32-0 ethyl (Z)-2,3-diphenyl-2-propenoate 
• 37428-50-5 (2E)-3-iodo-2-propen-1-ol 
• 1955-39-1 5-phenyl-3H-furan-2-one 
• 60112-29-0 5-cyclohexyl-5-hydrofuran-2-one 
• 37428-57-2 (Z)-3-iodoprop-2-en-1-ol 
• 165522-44-1 (Z)-1-Iodo-3-phenylprop-1-en-3-ol 
• 266325-19-3 ethyl 6-phenylhex-5-yn-(2Z)-enoate 
• 14251-57-1 1,1-diphenyl-1,2-propadiene 
• 266325-23-9 ethyl (E)-6-phenylhex-2-en-5-ynoate 
• 57042-08-7 Diethyl trans-hex-3-enedioate 
• 875758-56-8 cis-3-Hexendicarbonsaeurediaethylester 
• 6032-77-5 diethyl (2Z,4Z)-2,4-hexadienedioate 

Relevant articles and documents

Synthesis of 2E,4E,6E,11Z-octadecatetraenoic acid of the Rhizobium leguminosarum biovar viciae Nod factor

2E,4E,6E,11Z-Octadecatetraenoic acid was synthesized in a good yield and in a stereospecific manner by coupling a vinylborane compound and ethyl trans-3-iodoacrylate. The trienic system (E,E,E) was obtained by successive use of metal-catalyzed coupling and hydro-metallation reactions.

Substituent Effects in the Intramolecular Diels-Alder Reaction of 6-Furylhexenoates

The series of furyl enone esters, 4a-c, were synthesized from furan or furfural by straightforward routes. Their thermal intramolecular Diels-Alder reactions to give the tricyclic ketones 5a-c were studied in acetonitrile and toluene at two temperatures and the kinetics of the reactions determined. A comparison of these data with that obtained for the corresponding esters 2 to give the lactones 3 indicates that the rate enhancements seen for the esters (rate of dimethyl 310 times that of monomethyl) are much larger than those seen for the ketones (rate of dimethyl 6.8 times that of monomethyl). Thus, this is additional evidence for the earlier hypothesis that the presence of the oxygen atom in the tether is a factor responsible for the larger than normal rate enhancements.

Preparation method of selinexor and intermediate thereof

The invention relates to a preparation method of selinexor and an intermediate thereof, which has the advantages of short synthetic route, mild reaction conditions, no foul gas generation in the reaction process, high safety, wide acceptable range of vari

Total synthesis of selaginpulvilins A and C

An efficient formal total synthesis of two compounds from the selaginpulvilin family of natural products, selaginpulvilin A and C, has been successfully achieved. The tetradehydro Diels-Alder (TDDA) reaction between an enyne and alkyne has been utilized for the creation of the necessary fluorene skeleton. Attempts at the conversion of selaginpulvilin A to selaginpulvilin B, F and H were unsuccessful.