100511-00-0

Usage

Uses

Used in Chemical Research:
3,3-DiMethyl-5-nitroindolin-2-one is used as a fluorescent probe for [application reason], allowing researchers to track and study various chemical and biological processes due to its fluorescent properties.
Used in Organic Synthesis:
3,3-DiMethyl-5-nitroindolin-2-one is used as a building block in organic synthesis for [application reason], contributing to the creation of new compounds and materials with potential applications in various industries.
Used in Pharmaceutical Research:
3,3-DiMethyl-5-nitroindolin-2-one is used as a potential antioxidant for [application reason], exploring its ability to protect cells from oxidative damage and potentially contributing to the development of new therapeutic agents.
Used in Cancer Research:
3,3-DiMethyl-5-nitroindolin-2-one is used as an inhibitor of certain cancer cell lines for [application reason], with ongoing studies to understand its mechanism of action and its potential as a cancer treatment.
Used in Materials Science:
3,3-DiMethyl-5-nitroindolin-2-one is used in the development of new materials for [application reason], leveraging its chemical properties to create innovative materials with unique characteristics for various applications.

Upstream product

• 3078-04-4 isobutyraldehyde-(4-nitro-phenylhydrazone) 
• 19155-24-9 3,3-dimethyloxindole 
• 1504-06-9 3-methylindolin-2-one 

Downstream Products

• 925220-74-2 C₁₇H₁₅ClN₂O₃ 
• 925220-77-5 C₁₈H₁₈N₂O₅S 
• 120791-64-2 1-Benzyl-1,3-dihydro-3,3-dimethyl-5-nitro-2H-indol-2-one 
• 125089-31-8 N-(3,3-dimethyl-2-oxo-indolin-5-yl)-benzamide 
• 120791-65-3 N-Methyl-N-(1-benzyl-1,3-dihydro-2-oxo-3,3-dimethyl-2H-5-indolyl)formamide 
• 925220-72-0 5-Amino-1-benzyl-3,3-dimethyl-1,3-dihydro-indol-2-one 
• 31523-05-4 5-amino-3,3-dimethyl-2-indolinone 

Relevant academic research and scientific papers

Kinase inhibitors (by machine translation)

The present invention relates to certain 4 - (substituted anilino) -2 - (substituted piperi -1 -yl) pyrimidine -5 - carboxamide compounds useful for the treatment or prevention of diseases or medical conditions mediated by signal transduction of CaMMK1 isotype. For example, such compounds and salts thereof may be used to treat or prevent a variety of different cancers. Diseases (including 2 diabetes) and/or immune-mediated diseases. (by machine translation)

A pentacyclic aurora kinase inhibitor (AKI-001) with high in vivo potency and oral bioavailability

Aurora kinase inhibitors have attracted a great deal of interest as a new class of antimitotic agents. We report a novel class of Aurora inhibitors based on a pentacyclic scaffold. A prototype pentacyclic inhibitor 32 (AKI-001) derived from two early lead

Pentacyclic kinase inhibitors

The invention provides novel kinase inhibitors that are useful as therapeutic agents for example in the treatment malignancies where the compounds have the general formula I wherein A, X, Y, Z, Ra, Rb, Rc, R1, R2, R3 and m are defined herein.

PYRIMIDINE KINASE INHIBITORS

The invention provides novel kinase inhibitors that are useful as therapeutic agents for example in the treatment malignancies where the compounds have the general formula (I) wherein ring A, X, Y, Z, R1, R2, R3, R4, m and n are as defined herein.

Pyrrolobenzimidazoles for treating heart or circulatory diseases

Pyrrolobenzimidazoles, processes for the preparation thereof and pharmaceutical compositions thereof for the treatment of coronary insufficiencies, cardiac failure, blood circulatory disturbances and occlusive diseases. The new pyrrolobenzimidazoles are of the formula STR1 wherein R1 is hydrogen, alkyl, alkenyl or cycloalkyl, R2 is hydrogen, alkyl, alkenyl, cyano or a substituted carbonyl or R1 and R2 together represent cycloalkylene or form alkylidene or cycloalkylidene, X is a valency bond, C1 -C4 alkylene or vinylene, T is oxygen or sulphur and Py is pyridyl or substituted pyridyl and including the tautomers thereof and the physiologically acceptable salts thereof.