100511-00-0

Basic information

• Product Name: 3,3-DiMethyl-5-nitroindolin-2-one
• Synonyms: 3,3-DiMethyl-5-nitroindolin-2-one;1,3-dihydro-3,3-dimethyl-5-nitro-2H-indol-2-one;3,3-dimethyl-5-nitro-1H-indol-2-one
• CAS NO: 100511-00-0
• Molecular Formula: C₁₀H₁₀N₂O₃
• Molecular Weight: 206.198
• Mol File: 100511-00-0.mol
• Article Data: 5

Chemical Properties

• Boiling Point: 384.8±42.0 °C(Predicted)
• Appearance: /
• Density: 1.278±0.06 g/cm3(Predicted)
• Storage Temp.: Sealed in dry,Room Temperature
• PKA: 12.69±0.40(Predicted)
• CAS DataBase Reference: 3,3-DiMethyl-5-nitroindolin-2-one(CAS DataBase Reference)
• NIST Chemistry Reference: 3,3-DiMethyl-5-nitroindolin-2-one(100511-00-0)
• EPA Substance Registry System: 3,3-DiMethyl-5-nitroindolin-2-one(100511-00-0)

Safety Data

• Hazardous Substances Data: 100511-00-0(Hazardous Substances Data)

Usage

General Description

3,3-DiMethyl-5-nitroindolin-2-one is a chemical compound with the molecular formula C11H10N2O3. It is a yellow crystalline solid with a nitro group and a methyl group attached to the indolin-2-one ring. 3,3-DiMethyl-5-nitroindolin-2-one has been studied for its potential as a fluorescent probe and as a building block for organic synthesis. It has also been explored for its potential biological activities, including its role as a potential antioxidant and its ability to inhibit the growth of certain cancer cell lines. 3,3-DiMethyl-5-nitroindolin-2-one is of interest to researchers in the fields of chemistry, materials science, and medicinal chemistry due to its unique structure and potential applications.

Upstream product

• 19155-24-9 3,3-dimethyloxindole 
• 1504-06-9 3-methylindolin-2-one 
• 3078-04-4 isobutyraldehyde-(4-nitro-phenylhydrazone) 

Downstream Products

• 925220-77-5 C₁₈H₁₈N₂O₅S 
• 925220-74-2 C₁₇H₁₅ClN₂O₃ 
• 120791-64-2 1-Benzyl-1,3-dihydro-3,3-dimethyl-5-nitro-2H-indol-2-one 
• 125089-31-8 N-(3,3-dimethyl-2-oxo-indolin-5-yl)-benzamide 
• 120791-65-3 N-Methyl-N-(1-benzyl-1,3-dihydro-2-oxo-3,3-dimethyl-2H-5-indolyl)formamide 
• 925220-72-0 5-Amino-1-benzyl-3,3-dimethyl-1,3-dihydro-indol-2-one 
• 31523-05-4 5-amino-3,3-dimethyl-2-indolinone 

Relevant articles and documents

Kinase inhibitors (by machine translation)

The present invention relates to certain 4 - (substituted anilino) -2 - (substituted piperi -1 -yl) pyrimidine -5 - carboxamide compounds useful for the treatment or prevention of diseases or medical conditions mediated by signal transduction of CaMMK1 isotype. For example, such compounds and salts thereof may be used to treat or prevent a variety of different cancers. Diseases (including 2 diabetes) and/or immune-mediated diseases. (by machine translation)

Pentacyclic kinase inhibitors

The invention provides novel kinase inhibitors that are useful as therapeutic agents for example in the treatment malignancies where the compounds have the general formula I wherein A, X, Y, Z, Ra, Rb, Rc, R1, R2, R3 and m are defined herein.

Pyrrolobenzimidazoles for treating heart or circulatory diseases

Pyrrolobenzimidazoles, processes for the preparation thereof and pharmaceutical compositions thereof for the treatment of coronary insufficiencies, cardiac failure, blood circulatory disturbances and occlusive diseases. The new pyrrolobenzimidazoles are of the formula STR1 wherein R1 is hydrogen, alkyl, alkenyl or cycloalkyl, R2 is hydrogen, alkyl, alkenyl, cyano or a substituted carbonyl or R1 and R2 together represent cycloalkylene or form alkylidene or cycloalkylidene, X is a valency bond, C1 -C4 alkylene or vinylene, T is oxygen or sulphur and Py is pyridyl or substituted pyridyl and including the tautomers thereof and the physiologically acceptable salts thereof.