1005180-36-8

Basic information

• Product Name: N-((1R,2S,5R)-5-(methylamino)-2-((S)-2-oxo-3-((6-(trifluoromethyl)quinazolin-4-yl)amino)pyrrolidin-1-yl)cyclohexyl)acetamide
• Synonyms: N-((1R,2S,5R)-5-(methylamino)-2-((S)-2-oxo-3-((6-(trifluoromethyl)quinazolin-4-yl)amino)pyrrolidin-1-yl)cyclohexyl)acetamide
• CAS NO: 1005180-36-8
• Molecular Weight: 464.491
• Mol File: 1005180-36-8.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: N-((1R,2S,5R)-5-(methylamino)-2-((S)-2-oxo-3-((6-(trifluoromethyl)quinazolin-4-yl)amino)pyrrolidin-1-yl)cyclohexyl)acetamide(CAS DataBase Reference)
• NIST Chemistry Reference: N-((1R,2S,5R)-5-(methylamino)-2-((S)-2-oxo-3-((6-(trifluoromethyl)quinazolin-4-yl)amino)pyrrolidin-1-yl)cyclohexyl)acetamide(1005180-36-8)
• EPA Substance Registry System: N-((1R,2S,5R)-5-(methylamino)-2-((S)-2-oxo-3-((6-(trifluoromethyl)quinazolin-4-yl)amino)pyrrolidin-1-yl)cyclohexyl)acetamide(1005180-36-8)

Safety Data

• Hazardous Substances Data: 1005180-36-8(Hazardous Substances Data)

Upstream product

• 1005180-90-4 N-((1R,2S,5R)-2-((S)-3-amino-2-oxopyrrolidin-1-yl)-5-(methylamino)cyclohexyl)acetamide 
• 16499-64-2 4-chloro-6-(trifluoromethyl)quinazoline 

Relevant articles and documents

Discovery of BMS-753426: A Potent Orally Bioavailable Antagonist of CC Chemokine Receptor 2

To improve the metabolic stability profile of BMS-741672 (1a), we undertook a structure-activity relationship study in our trisubstituted cyclohexylamine series. This ultimately led to the identification of 2d (BMS-753426) as a potent and orally bioavaila