100519-08-2Relevant academic research and scientific papers
Enantioselective Three-Component Fluoroalkylarylation of Unactivated Olefins through Nickel-Catalyzed Cross-Electrophile Coupling
Tu, Hai-Yong,Wang, Fang,Huo, Liping,Li, Yuanbo,Zhu, Shengqing,Zhao, Xian,Li, Huan,Qing, Feng-Ling,Chu, Lingling
supporting information, p. 9604 - 9611 (2020/07/14)
A nickel-catalyzed, enantioselective, three-component fluoroalkylarylation of unactivated alkenes with aryl halides and perfluoroalkyl iodides has been described. This cross-electrophile coupling protocol utilizes a chiral nickel/BiOx system as well as a pendant chelating group to facilitate the challenging three-component, asymmetric difunctionalization of unactivated alkenes, providing direct access to valuable chiral β-fluoroalkyl arylalkanes with high efficiency and excellent enantioselectivity. The mild conditions allow for a broad substrate scope as well as good functional group toleration.
METHOD FOR MANUFACTURING P-HYDROXY BENZOIC ACID ALLYL POLYMER
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Paragraph 0045, (2017/02/24)
PROBLEM TO BE SOLVED: To provide a method for efficiently manufacturing p-hydroxy benzoic acid allyl polymer having high antibacterial property. SOLUTION: There is provided a method for manufacturing p-hydroxy benzoic acid allyl polymer including (A) a pr
Palladium-catalyzed allylic esterification via C-C bond cleavage of a secondary homoallyl alcohol
Wang, Yong,Kang, Qiang
supporting information, p. 4190 - 4193 (2014/10/15)
Palladium-catalyzed allylic esterifications of secondary homoallyl alcohols with acids via sequential retro-allylation and esterification are demonstrated, affording the corresponding allyl ester in up to 99% yield. The electron effect of the substituent of the secondary alcohol was found to be crucial to the selective C-C bond cleavage.
