1005475-16-0

Upstream product

• 122663-22-3 (R)-5-(hydroxymethyl)-1-methylpyrrolidin-2-one 
• 98-59-9 p-toluenesulfonyl chloride 
• 66673-40-3 (R)-5-hydroxymethylpyrrolidin-2-one 
• 128899-31-0 <(2R)-5-oxopyrrolidin-2-yl>methyl 4-methylbenzenesulfonate 
• 74-88-4 methyl iodide 

Relevant academic research and scientific papers

ANTICANCER PYRIDOPYRAZINES VIA THE INHIBITION OF FGFR KINASES

The invention relates to new pyridopyrazine derivative compounds, to pharmaceutical compositions comprising said compounds, to processes for the preparation of said compounds and to the use of said compounds in the treatment of diseases, e.g. cancer.

2-PYRIDONE COMPOUNDS

A 2-pyridone compound represented by the formula [1]: {wherein in the formula [1], the ring represented by A represents a benzene ring or a pyridine ring, X represents any of the structures represented by the formulas [3] shown below: V represents a single bond or a lower alkylene group, and W represents a single bond, an ether bond or a lower alkylene group (wherein the lower alkylene group may contain an ether bond)}, a tautomer or stereoisomer of the compound, a pharmaceutically acceptable salt thereof, or a solvate thereof is a compound that has an excellent GK activating effect and is useful as a pharmaceutical.