100561-49-7Relevant academic research and scientific papers
Stereoselective Epoxidations and Electrophilic Additions to Partial Ergot Alkaloids and Conformationally-Fixed Styrenes. Experimental and Theoretical Modeling Evidence for the Importance of Torsional Steering as a Stereocontrol Element
Martinelli, Michael J.,Peterson, Barry C.,Khau, Vien V.,Hutchison, Darrell R.,Leanna, M. Robert,et al.
, p. 2204 - 2210 (2007/10/02)
Partial ergot alkaloid substrates and related conformationally-fixed styrenes undergo epoxidation, osmium tetraoxide dihydroxylation, and hydrobromination with a level of stereoselectivity which cannot be explained by steric control but is consistent with
6-SUBSTITUTED-4-DIALKYLAMINOTETRAHYDROBENZ(C,D)INDOLES
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, (2008/06/13)
(.+-.)-4-substitutedamino-6-alkoxy, benzyloxy, acyloxy, or hydroxy-1,3, 4,5-tetrahydrobenz[c,d]indoles, pharmaceutically acceptable salts thereof, are anti-depressants.
6-Substituted 1,3,4,5-tetrahydrobenz[cd]indol-4-amines: Potent serotonin agonists
Flaugh,Mullen,Fuller,Mason
, p. 1746 - 1753 (2007/10/02)
A series of 6-substituted tricyclic ergoline partial structures has been synthesized and found to possess very strong serotonin agonist activity. A methoxy group at the 6-position greatly enhances activity, but at the expense of compound stability. Substi
