10057-46-2

Usage

Uses

Used in Pharmaceutical and Agrochemical Synthesis:
5-Trifluoromethyl-1H-benzoimidazol-2-ylamine is utilized as a key intermediate in the synthesis of various pharmaceuticals and agrochemicals. Its unique structure and properties contribute to the development of novel compounds with potential therapeutic and pesticidal effects.
Used in Research and Development:
5-TRIFLUOROMETHYL-1H-BENZOIMIDAZOL-2-YLAMINE plays a significant role in the research and development of new chemical products. Its versatile chemical properties allow for the exploration of its potential applications in various fields, including medicine, agriculture, and materials science.
Used as a Reagent in Organic Chemistry:
5-Trifluoromethyl-1H-benzoimidazol-2-ylamine is employed as a reagent in organic chemistry for the modification of other molecules. It is used to introduce the 5-trifluoromethyl-1H-benzoimidazol-2-ylamine moiety into target molecules, enhancing their properties and functionalities for specific applications.

InChI:InChI=1/C8H6F3N3/c9-8(10,11)4-1-2-5-6(3-4)14-7(12)13-5/h1-3H,(H3,12,13,14)

Upstream product

• 506-68-3 bromocyane 
• 368-71-8 4-(trifluoromethyl)-1,2-phenylenediamine 
• 400-98-6 4-trifluoromethyl-2-nitroaniline 

Downstream Products

• 1446200-49-2 2-(2-(trifluoromethoxy)benzamido)-N-(6-(trifluoromethyl)-1H-benzo[d]imidazol-2-yl)thiazole-4-carboxamide 
• 1616406-41-7 2-(2-amino-5-(trifluoromethyl)-1H-benzo[d]imidazol-1-yl)-1-(2-chloro-4-(trifluoromethyl)phenyl)ethanol 
• 1616405-94-7 2-(2-amino-6-(trifluoromethyl)-1H-benzo[d]imidazol-1-yl)-1-(2-chloro-4-(trifluoromethyl)phenyl)ethanol 
• 1616406-39-3 2-(2-amino-6-(trifluoromethyl)-1H-benzo[d]imidazol-1-yl)-1-(2-chloro-4-(trifluoromethyl)phenyl)ethanone 
• 1616406-40-6 C₁₇H₁₀ClF₆N₃O 

Relevant academic research and scientific papers

BENZIMIDAZOLE DERIVATIVES AS RAF KINASE INHIBITORS

The present invention relates to benzimidazole derivatives of formula I, the use of the compounds of formula I as inhibitors of one or more kinases, the use of the compounds of formula I for the manufacture of a pharmaceutical composition and a method of treatment, comprising administering said pharmaceutical composition to a patient. Accordingly, the compound of Formula I or a pharmaceutically acceptable salt thereof is administered for the treatment of diseases mediated by one or more kinase pathways, preferably by the raf kinase pathway, especially cancers, [FORMULA]

Substituted 1-sulfonylbenzimidazoles

Certain 1-sulfonyl-2,5(6)-substituted-benzimidazole compounds are useful as antiviral agents.