1005786-63-9

Basic information

• Product Name: 4-(2-{[tert-butyl(dimethyl)silyl]oxy}-1,1-dimethylethyl)-N-[6-(1H-imidazol-1-yl)imidazo[1,2-a]pyridin-2-yl]benzamide
• Synonyms: 4-(2-{[tert-butyl(dimethyl)silyl]oxy}-1,1-dimethylethyl)-N-[6-(1H-imidazol-1-yl)imidazo[1,2-a]pyridin-2-yl]benzamide
• CAS NO: 1005786-63-9
• Molecular Weight: 489.693
• Mol File: 1005786-63-9.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 4-(2-{[tert-butyl(dimethyl)silyl]oxy}-1,1-dimethylethyl)-N-[6-(1H-imidazol-1-yl)imidazo[1,2-a]pyridin-2-yl]benzamide(CAS DataBase Reference)
• NIST Chemistry Reference: 4-(2-{[tert-butyl(dimethyl)silyl]oxy}-1,1-dimethylethyl)-N-[6-(1H-imidazol-1-yl)imidazo[1,2-a]pyridin-2-yl]benzamide(1005786-63-9)
• EPA Substance Registry System: 4-(2-{[tert-butyl(dimethyl)silyl]oxy}-1,1-dimethylethyl)-N-[6-(1H-imidazol-1-yl)imidazo[1,2-a]pyridin-2-yl]benzamide(1005786-63-9)

Safety Data

• Hazardous Substances Data: 1005786-63-9(Hazardous Substances Data)

Upstream product

• 1005785-98-7 ethyl 4-(2-{[tert-butyl(dimethyl)silyl]oxy}-1,1-dimethylethyl)benzoate 
• 1005786-00-4 4-(2-{[tert-butyl(dimethyl)silyl]oxy}-1,1-dimethylethyl)benzoic acid 
• 1710-98-1 p-tert-butyl benzoyl chloride 
• 288-32-4 1H-imidazole 
• 1005786-60-6 4-(2-{[tert-butyl(dimethyl)silyl]oxy}-1,1-dimethylethyl)-N-(6-iodoimidazo[1,2-a]pyridin-2-yl)benzamide 
• 1005786-45-7 4-(2-{[tert-butyl(dimethyl)silyl]oxy}-1,1-dimethylethyl)benzoyl chloride 
• 1005775-53-0 4-tert-butyl-N-(6-iodoimidazo[1,2-a]pyridin-2-yl)benzamide 

Downstream Products

• 1005776-06-6 4-(2-hydroxy-1,1-dimethylethyl)-N-[6-(1H-imidazol-1-yl)imidazo[1,2-a]pyridin-2-yl]benzamide 

Relevant articles and documents

Design and biological evaluation of imidazo[1,2-a]pyridines as novel and potent ASK1 inhibitors

Imidazo[1,2-a]pyridine derivatives were designed, synthesized, and evaluated as inhibitors of the apoptosis signal-regulating kinase 1 (ASK1). These were based on a benzothiazole derivative that was discovered from high-throughput screening of our compound library. As a result, we identified potent, selective, and orally bioavailable ASK1 inhibitors for wide range of therapeutic targets.