1005789-27-4Relevant academic research and scientific papers
Halogen-containing heteroaromatic carbenes of the 1,2,4-triazole series and their transformations
Glinyanaya, Nataliya V.,Korotkikh, Nikolai I.,Rayenko, Gennady F.,Rusanov, Eduard B.,Ryabitsky, Alexey B.,Shvaika, Oles P.
, p. 30841 - 30848 (2021/11/17)
A series of new stable halogenated carbenes, 1-tert-butyl-3,4-diaryl-1,2,4-triazol-5-ylidenes, has been synthesized. According to quantum chemical calculations, 4-(2,3,4-trifluorophenyl)-substituted 1-tert-butyl-3,4-diaryl-1,2,4-triazol-5-ylidene is the l
Reaction of 1-tert-butyl-3,4-diphenyl-1,2,4-triazol-5-ylidenes with a malonic ester
Korotkikh, Nikolai I.,Cowley, Alan H.,Moore, Jennifer A.,Glinyanaya, Nataliya V.,Panov, Ilia S.,Rayenko, Gennady F.,Pekhtereva, Tatyana M.,Shvaika, Oles P.
, p. 195 - 199 (2008/09/20)
Four stable carbenes, 1-tert-butyl-3,4-diaryl-1,2,4-triazol-5-ylidenes 1a-d, including new fluorine-containing compounds 1c,d, react with a malonic ester to afford heterocyclic zwitterionic compounds 5a-d. The reactions with more acidic compounds (ethyl acetoacetate, malononitrile and 1,3-dimethylbarbituric acid) proceed with substrate deprotonation to form the respective azolium salts 6a-c. The X-ray crystal structure of 5a was also determined. The Royal Society of Chemistry 2008.
