1006-22-0 Usage
General Description
1,7-Dihydro-1-methyl-6H-purine-6-thione, also known as 1-Methyl-1,7-dihydro-6H-purine-6-thione, is a chemical compound belonging to the purine family. It is a sulfur-containing derivative of purine and is commonly found in coffee, tea, and chocolate. 1,7-Dihydro-1-methyl-6H-purine-6-thione has been studied for its potential therapeutic effects, including its antioxidant, anti-inflammatory, and neuroprotective properties. It may also have potential applications in the treatment of neurodegenerative diseases and cancer. Additionally, 1,7-Dihydro-1-methyl-6H-purine-6-thione has been investigated for its role in the modulation of cell signaling pathways and its potential as a drug lead for the development of new pharmaceuticals.
Check Digit Verification of cas no
The CAS Registry Mumber 1006-22-0 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 1,0,0 and 6 respectively; the second part has 2 digits, 2 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 1006-22:
(6*1)+(5*0)+(4*0)+(3*6)+(2*2)+(1*2)=30
30 % 10 = 0
So 1006-22-0 is a valid CAS Registry Number.
InChI:InChI=1/C6H6N4S/c1-10-3-9-5-4(6(10)11)7-2-8-5/h2-3H,1H3,(H,7,8)
1006-22-0Relevant articles and documents
Synthesis of a peptide nucleic acid with a novel 1-methyl-6-mercaptopurine base
Aboul-Fadl, Tarek,Rajeev, Gopalan,Broom, Arthur D.
, p. 445 - 451 (2008/09/19)
(Chemical Equation Presented) A novel peptide nucleic acid (PNA) monomer 16 containing a novel 1-methyl-6-mercaptopurine base was synthesized by coupling the in situ generated acid chloride of (1-methyl-6-mercaptopurin-9-yl)acetic acid (6) into an L-lysine backbone (13) using 10% CCl4 in pyridine and Ph3P. Compound 6 was synthesized from 6-mercapto-1-methylpurine and ethylbromoacetate in the presence of NaH followed by alkaline hydrolysis and subsequent neutralization with a cation exchange resin. The L-lysine backbone (13) was obtained by the reaction of Nε-CBZ-L-lysine allyl ester with Boc-aminoactaldehyde in the presence of NaBH3CN under reductive amination conditions. Oligomerization of the monomer 16 to PNA analogues was achieved using BOC-BHA-PEG-PS resin as a solid support and the in situ generated acid chloride of 16 by 10% CCl4 in DCM in the presence of Ph 3P.
