1006-22-0 Usage
Uses
Used in Pharmaceutical Development:
1,7-Dihydro-1-methyl-6H-purine-6-thione is utilized as a drug lead for the development of new pharmaceuticals, leveraging its potential therapeutic effects for the treatment of various conditions.
Used in Neurodegenerative Disease Treatment:
In the medical field, 1,7-Dihydro-1-methyl-6H-purine-6-thione is used as a neuroprotective agent, owing to its potential to shield neurons from damage and degeneration, making it a candidate for treating neurodegenerative diseases.
Used in Cancer Therapy:
1,7-Dihydro-1-methyl-6H-purine-6-thione is also considered for use as an anticancer agent, given its possible role in the treatment of cancer by affecting cellular processes.
Used in Antioxidant and Anti-Inflammatory Applications:
1,7-Dihydro-1-methyl-6H-purine-6-thione is used in antioxidant and anti-inflammatory applications due to its inherent properties that may help combat oxidative stress and reduce inflammation.
Used in Food and Beverage Industry:
In the food and beverage industry, 1,7-Dihydro-1-methyl-6H-purine-6-thione is naturally found in coffee, tea, and chocolate, contributing to their characteristic flavors and potentially offering health benefits associated with its chemical properties.
Used in Research:
1,7-Dihydro-1-methyl-6H-purine-6-thione is used in scientific research for studying its role in modulating cell signaling pathways, which could lead to a better understanding of its mechanisms of action and potential applications in medicine.
Check Digit Verification of cas no
The CAS Registry Mumber 1006-22-0 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 1,0,0 and 6 respectively; the second part has 2 digits, 2 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 1006-22:
(6*1)+(5*0)+(4*0)+(3*6)+(2*2)+(1*2)=30
30 % 10 = 0
So 1006-22-0 is a valid CAS Registry Number.
InChI:InChI=1/C6H6N4S/c1-10-3-9-5-4(6(10)11)7-2-8-5/h2-3H,1H3,(H,7,8)
1006-22-0Relevant academic research and scientific papers
Synthesis of a peptide nucleic acid with a novel 1-methyl-6-mercaptopurine base
Aboul-Fadl, Tarek,Rajeev, Gopalan,Broom, Arthur D.
, p. 445 - 451 (2008/09/19)
(Chemical Equation Presented) A novel peptide nucleic acid (PNA) monomer 16 containing a novel 1-methyl-6-mercaptopurine base was synthesized by coupling the in situ generated acid chloride of (1-methyl-6-mercaptopurin-9-yl)acetic acid (6) into an L-lysine backbone (13) using 10% CCl4 in pyridine and Ph3P. Compound 6 was synthesized from 6-mercapto-1-methylpurine and ethylbromoacetate in the presence of NaH followed by alkaline hydrolysis and subsequent neutralization with a cation exchange resin. The L-lysine backbone (13) was obtained by the reaction of Nε-CBZ-L-lysine allyl ester with Boc-aminoactaldehyde in the presence of NaBH3CN under reductive amination conditions. Oligomerization of the monomer 16 to PNA analogues was achieved using BOC-BHA-PEG-PS resin as a solid support and the in situ generated acid chloride of 16 by 10% CCl4 in DCM in the presence of Ph 3P.
Synthesis and pharmacological activity of triazolo[1,5-α]triazine derivatives inhibiting eosinophilia
Akahoshi, Fumihiko,Takeda, Shinji,Okada, Takehiro,Kajii, Masahiko,Nishimura, Hiroko,Sugiura, Masanori,Inoue, Yoshihisa,Fukaya, Chikara,Naito, Youichiro,Imagawa, Takashi,Nakamura, Norifumi
, p. 2985 - 2993 (2007/10/03)
In continuation of our previous work on eosinophilia inhibitors, we synthesized an additional series of inhibitors, which consisted of 5-amino- 1-[(methylamino)thiocarbonyl]-1H-1,2,4-triazole derivatives and a newly developed series of 1,2,4-triazolo[1,5-
