1006059-94-4

Basic information

• Product Name: [2-(2,2-dichloro-1-methylvinyl)-4-nitrophenyl]methylamine
• Synonyms: [2-(2,2-dichloro-1-methylvinyl)-4-nitrophenyl]methylamine
• CAS NO: 1006059-94-4
• Molecular Weight: 261.108
• Mol File: 1006059-94-4.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: [2-(2,2-dichloro-1-methylvinyl)-4-nitrophenyl]methylamine(CAS DataBase Reference)
• NIST Chemistry Reference: [2-(2,2-dichloro-1-methylvinyl)-4-nitrophenyl]methylamine(1006059-94-4)
• EPA Substance Registry System: [2-(2,2-dichloro-1-methylvinyl)-4-nitrophenyl]methylamine(1006059-94-4)

Safety Data

• Hazardous Substances Data: 1006059-94-4(Hazardous Substances Data)

Upstream product

• 1006059-93-3 2-(2,2-dichloro-1-methylvinyl)-1-fluoro-4-nitrobenzene 
• 74-89-5 methylamine 

Downstream Products

• 1006059-95-5 1,3-dimethyl-5-nitro-2-phenyl-1H-indole 

Relevant articles and documents

A highly selective tandem cross-coupling of gem-dihaloolefins for a modular, efficient synthesis of highly functionalized indoles

(Chemical Equation Presented) A highly efficient method of indole synthesis using gem-dihalovinylaniline substrates and an organoboron reagent was developed via a Pd-catalyzed tandem intramolecular amination and an intermolecular Suzuki coupling. Aryl, alkenyl, and alkyl boron reagents are all successfully employed, making for a versatile modular approach. The reaction tolerates a variety of substitution patterns on the aniline leading to indoles with group at C2-C7. The orthogonal approach of the sequential copper- and palladium-mediated synthesis of 1,2-diarylindoles exploited the wide availability of diverse organoboron reagents.