100622-15-9

Upstream product

• 91925-82-5 3,5-dihydroxy-4-(phenylmethoxy)benzoic acid methyl ester 
• 102019-30-7 4-O-benzyl-3,5-diacetoxybenzoic acid methyl ester 
• 20189-90-6 3,4,5-triacetoxy-benzoic acid methyl ester 
• 100-44-7 benzyl chloride 
• 100-39-0 benzyl bromide 
• 99-24-1 methyl galloate 

Downstream Products

• 1399278-42-2 4-(benzyloxy)-3,5-bis((tert-butyldimethylsilyl)oxy)benzoic acid 
• 147801-01-2 4-Benzyloxy-3,5-bis-heptyloxy-N,N-dimethyl-benzamide 
• 147801-00-1 4-Benzyloxy-3,5-bis-hexyloxy-N,N-dimethyl-benzamide 
• 147801-03-4 4-Benzyloxy-3,5-bis-cyclopentyloxy-N,N-dimethyl-benzamide 
• 147800-99-5 4-Benzyloxy-N,N-dimethyl-3,5-bis-pentyloxy-benzamide 
• 147801-04-5 4-Benzyloxy-3,5-bis-(1-ethyl-propoxy)-N,N-dimethyl-benzamide 
• 147800-98-4 4-Benzyloxy-3,5-dibutoxy-N,N-dimethyl-benzamide 
• 147800-97-3 4-Benzyloxy-N,N-dimethyl-3,5-dipropoxy-benzamide 
• 147801-02-3 4-Benzyloxy-3,5-diisopropoxy-N,N-dimethyl-benzamide 

Relevant academic research and scientific papers

Synthetic studies toward c-glucosidic ellagitannins: A biomimetic total synthesis of 5-O-desgalloylepipunicacortein A

C-glucosidic ellagitannins constitute a subclass of bioactive polyphenolic natural products with strong antioxidant properties, as well as promising antitumoral and antiviral activities that are related to their capacity to interact with both functional and structural proteins. To date, most synthetic efforts toward ellagitannins have concerned glucopyranosic species. The development of a synthetic strategy to access C-glucosidic ellagitannins, whose characteristic structural feature includes an atropoisomeric hexahydroxydiphenoyl (HHDP) or a nonahydroxyterphenoyl (NHTP) unit that is linked to an open-chain glucose core by a C-aryl glucosidic bond, is described herein. The total synthesis of the biarylic HHDP-containing 5-O- desgalloylepipunicacortein A (1 β) was achieved by either using the natural ellagic acid bis-lactone as a precursor of the requested HHDP unit or by implementing an atroposelective intramolecular oxidative biarylic coupling to forge this HHDP unit. Both routes converged in the penultimate step of this synthesis to enable a biomimetic formation of the key C-aryl glucosidic bond in the title compound.

Benzylamine Antioxidants: Relationship between Structure, Peroxyl Radical Scavenging, Lipid Peroxidation Inhibition, and Cytoprotection

Three homologous series of 3,5-dialkoxy-4-hydroxybenzylamines were prepared and tested (1) as peroxyl radical scavengers in homogeneous aqueous solution, (2) as inhibitors of iron-dependent peroxidation of rabbit brain vesicular membrane lipids, and (3) a