10063-16-8 Usage
Chemical compound
17-(dimethylamino)androst-4-en-3-one is a synthetic chemical compound.
Structural similarity
It is structurally similar to amphetamines.
Common use
It is commonly used as a stimulant and fat-burning agent in dietary supplements and workout products.
Original development
DMAA was originally developed as a decongestant and isomer of amphetamine.
Ban
It has been banned by several countries due to concerns about its safety and potential negative side effects.
Side effects
These include increased heart rate, high blood pressure, and even stroke.
Unregulated ingredient
Despite being banned, DMAA is still often found in "pre-workout" supplements as an unregulated ingredient.
Risk
This leads to a continued risk for adverse health effects among consumers.
Controversy
The use and availability of DMAA in dietary supplements and workout products remains a topic of controversy and concern within the health and fitness industry.
Check Digit Verification of cas no
The CAS Registry Mumber 10063-16-8 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,0,0,6 and 3 respectively; the second part has 2 digits, 1 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 10063-16:
(7*1)+(6*0)+(5*0)+(4*6)+(3*3)+(2*1)+(1*6)=48
48 % 10 = 8
So 10063-16-8 is a valid CAS Registry Number.
10063-16-8Relevant academic research and scientific papers
Steroids and Related Studies: Part 82 - Chandonium Related Azasteroidal Neuromuscular Blockers
Singh, Harkishan,Gupta, Rakesh Kumar,Bhardwaj, Tilak Raj
, p. 508 - 512 (2007/10/02)
Modelled on clinically active chandonium iodide (1) different azasteroidal neuromuscular blockers have been designed. 17β-Dimethylamino-3β-pyrrolidino-5-androstene dimethiodide (HS-854) (2), having not the 17a-aza-D-homo system but extranuclear quaternary ammonium head with nearly equivalent steric placement, and the 17β-dimethylamino-3α-pyrrolidino-5-androstene dimethiodide (HS-1046) (dimethiodide of 6) have been synthesized. 17β-Dimethylamino-3β-pyrrolidino-5α-androstane dimethiodide (HS-944) (7) is the dihydro analogue of HS-854 (2).The other modification, viz 6-hydroxymethyl-17β-dimethylamino-3β-pyrrolidino-5-androstene dimethiodide (HS-892) (13) has a sterically significant substituent at position-6 which should also alter hydrophilic-lipophilic balance.All the new bisquaternary steroids are active as neuromuscular blockers in the rat phrenic nerve diaphragm preparation.The structure-activity relationship has been discussed.
