1006381-74-3Relevant academic research and scientific papers
Synthesis of 3′-azido-2′,3′-dideoxy-5-fluorouridine phosphoramidates and evaluation of their anticancer activity
Lewandowska, Marta,Ruszkowski, Piotr,Baraniak, Dagmara,Czarnecka, Anna,Kleczewska, Natalia,Celewicz, Lech
, p. 188 - 195 (2013/10/01)
A series of novel 4-chlorophenyl N-alkyl phosphoramidates of 3′-azido-2′,3′-dideoxy-5-fluorouridine (12-21) were synthesized by means of phosphorylation of 3′-azido-2′,3′- dideoxy-5-fluorouridine (4) with 4- chlorophenyl phosphoroditriazolide (10) followe
Regioselective acylation of nucleosides and their analogs catalyzed by Pseudomonas cepacia lipase: enzyme substrate recognition
Li, Ning,Zong, Min-Hua,Ma, Ding
supporting information; experimental part, p. 1063 - 1068 (2009/04/11)
The substrate recognition of Pseudomonas cepacia lipase in the acylation of nucleosides was investigated by means of rational substrate engineering for the first time. P. cepacia lipase displayed excellent 3′-regioselectivities (96 to >99%) in the lauroyl
