1006593-31-2Relevant academic research and scientific papers
Palladium-catalyzed carbonylative cross-coupling with imines: A multicomponent synthesis of imidazolones
Siamaki, Ali R.,Black, Daniel A.,Arndtsen, Bruce A.
, p. 1135 - 1138 (2008/09/18)
(Chemical Equation Presented) The palladium-catalyzed coupling of imines, chloroformates, organotin reagents, and carbon monoxide leads to the one-pot formation of ketocarbamates in good yields. These products can further be converted to highly substituted imidazolones via a cyclocondensation reaction. Overall, this methodology provides an alternative approach to imidazolones from five simple and readily available building blocks via a one-pot, multicomponent process.
