1006705-00-5Relevant academic research and scientific papers
A highly regioselective cyanothiolation of alkynes via oxidative addition of thiocyanates to tetrakis(triphenylphosphine)palladium(0) catalyst
Kamiya, Ikuyo,Kawakami, Jun-Ichi,Yano, Shigenobu,Nomoto, Akihiro,Ogawa, Akiya
, p. 3562 - 3564 (2006)
Tetrakis(triphenylphosphine)palladium(0) catalyzes the highly regioselective addition of phenyl thiocyanate (PhSCN) to terminal alkynes, which attains the simultaneous introduction of thio and cyano groups to the internal and terminal positions of alkynes, respectively. This reaction may proceed via the oxidative addition of PhSCN to Pd(PPh3)4, which forms Pd(SPh)(CN)(PPh3)2 as the key intermediate.
Transition-metal-catalyzed cyanochalcogenation of alkynes with chalcogenocyanates
Ozaki, Toshiya,Nomoto, Akihiro,Kamiya, Ikuyo,Kawakami, Jun-Ichi,Ogawa, Akiya
, p. 155 - 163 (2011/04/16)
Tetrakis(triphenylphosphine)palladium(0) catalyzes the highly regioselective addition of phenyl thiocyanate to terminal alkynes, which attains the simultaneous introduction of thio and cyano groups into the internal and terminal positions of alkynes, respectively. In addition, dicobalt octacarbonyl indicates moderate catalytic activity toward the same cyanothiolation of alkynes with excellent regioselectivity. By using [Co2(CO)8] as the catalyst, novel cyanoselenation of alkynes with phenyl selenocyanate has also been attained in moderate yield with excellent regioselectivity.
