1006907-48-7Relevant academic research and scientific papers
New selective carbonic anhydrase IX inhibitors: Synthesis and pharmacological evaluation of diarylpyrazole-benzenesulfonamides
Rogez-Florent, Tiphaine,Meignan, Samuel,Foulon, Catherine,Six, Perrine,Gros, Abigaelle,Bal-Mahieu, Christine,Supuran, Claudiu T.,Scozzafava, Andrea,Frederick, Raphael,Masereel, Bernard,Depreux, Patrick,Lansiaux, Amelie,Goossens, Jean-Francois,Gluszok, Sebastien,Goossens, Laurence
, p. 1451 - 1464 (2013/04/10)
Carbonic anhydrase (CA) IX expression is increased upon hypoxia and has been proposed as a therapeutic target since it has been associated with poor prognosis, tumor progression and pH regulation. We report the synthesis and the pharmacological evaluation
HETEROCYCLES USEFUL AS INHIBITORS OF CARBONIC ANHYDRASE
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Page/Page column 195, (2008/06/13)
Sulfonamides and pharmaceutical compositions containing the compounds useful in controlling intraocular pressure are disclosed. Methods for controlling intraocular pressure through administration of the compositions are also disclosed.
