100710-49-4 Usage
Uses
Used in Organic Synthesis:
2,4,5-trimethyl-1-phenyl-1H-pyrrole-3-carbaldehyde is used as a reactive intermediate in organic synthesis for the creation of a variety of complex organic molecules. Its aldehyde group allows for a range of reactions, such as reduction, oxidation, and condensation, which are essential in building up more intricate molecular structures.
Used in Medicinal Chemistry:
In the field of medicinal chemistry, 2,4,5-trimethyl-1-phenyl-1H-pyrrole-3-carbaldehyde is utilized as a building block for the development of novel pharmaceutical compounds. Its unique structure and reactivity make it a promising candidate for the synthesis of new drugs with potential therapeutic applications.
Used as a Precursor for Complex Molecules:
2,4,5-trimethyl-1-phenyl-1H-pyrrole-3-carbaldehyde serves as a precursor in the synthesis of more complex molecules, which may have applications in various industries. Its structural complexity and reactivity make it a valuable component in the creation of advanced materials and compounds with specific properties tailored for different uses.
Used in Various Industrial and Scientific Fields:
Due to its structural complexity and reactivity, 2,4,5-trimethyl-1-phenyl-1H-pyrrole-3-carbaldehyde may find applications across a wide range of industrial and scientific fields. Its potential uses could include the development of new materials, catalysts, or even in the creation of new chemical processes that leverage its unique properties.
Check Digit Verification of cas no
The CAS Registry Mumber 100710-49-4 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,0,0,7,1 and 0 respectively; the second part has 2 digits, 4 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 100710-49:
(8*1)+(7*0)+(6*0)+(5*7)+(4*1)+(3*0)+(2*4)+(1*9)=64
64 % 10 = 4
So 100710-49-4 is a valid CAS Registry Number.
100710-49-4Relevant academic research and scientific papers
Discovery and structure-activity relationships of pyrrolone antimalarials
Murugesan, Dinakaran,Mital, Alka,Kaiser, Marcel,Shackleford, David M.,Morizzi, Julia,Katneni, Kasiram,Campbell, Michael,Hudson, Alan,Charman, Susan A.,Yeates, Clive,Gilbert, Ian H.
supporting information, p. 2975 - 2990 (2013/05/23)
In the pursuit of new antimalarial leads, a phenotypic screening of various commercially sourced compound libraries was undertaken by the World Health Organisation Programme for Research and Training in Tropical Diseases (WHO-TDR). We report here the detailed characterization of one of the hits from this process, TDR32750 (8a), which showed potent activity against Plasmodium falciparum K1 (EC50 ～ 9 nM), good selectivity (>2000-fold) compared to a mammalian cell line (L6), and significant activity against a rodent model of malaria when administered intraperitoneally. Structure-activity relationship studies have indicated ways in which the molecule could be optimized. This compound represents an exciting start point for a drug discovery program for the development of a novel antimalarial.
