1007100-27-7Relevant academic research and scientific papers
Convenient divergent strategy for the synthesis of TunePhos-type chiral diphosphine ligands and their applications in highly enantioselective Ru-catalyzed hydrogenations
Sun, Xianfeng,Zhou, Le,Li, Wei,Zhang, Xumu
, p. 1143 - 1146 (2008)
(Chemical Equation Presented) A convenient, divergent strategy for the synthesis of a series of modular and fine-tunable C3-TunePhos-type chiral diphosphine ligands and their applications in highly efficient Rucatalyzed asymmetric hydrogenations were explored. Up to 97 and 99% ee values were achieved for the enantioselective synthesis of β-methyl chiral amines and α-hydroxy acid derivatives, respectively.
