1007125-09-8Relevant articles and documents
Stereoselective synthesis of 2′-fluoro-6′-methylene carbocyclic adenosine via Vince lactam
Singh, Uma S.,Mishra, Ram C.,Shankar, Ravi,Chu, Chung K.
, p. 3917 - 3923 (2014/05/20)
2′-Fluoro-6′-methylene carbocyclic adenosine (FMCA) is a potent and selective inhibitor of wild type as well as drug-resistant hepatitis B virus (HBV) mutants. FMCA demonstrated excellent anti-HBV activity against both adefovir-resistant and lamivudine-re
Heteroaryl compounds useful as inhibitors of E1 activating enzymes
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, (2008/06/13)
This invention relates to compounds that inhibit E1 activating enzymes, pharmaceutical compositions comprising the compounds, and methods of using the compounds. The compounds are useful for treating disorders, particularly cell proliferation disorders, including cancers, inflammatory and neurodegenerative disorders; and inflammation associated with infection and cachexia.