1007130-10-0Relevant articles and documents
Rhodium-catalyzed asymmetric hydroformylation of 1,1-disubstituted allylphthalimides: A catalytic route to β3-amino acids
Zheng, Xin,Cao, Bonan,Liu, Tang-Lin,Zhang, Xumu
supporting information, p. 679 - 684 (2013/04/10)
The high enantioselective rhodium-catalyzed hydroformylation of 1,1-disubstituted allylphthalimides has been developed. By employing chiral ligand 1,2-bis[(2S,5S)-2,5-diphenylphospholano]ethane [(S,S)-Ph-BPE], a series of β3-aminoaldehydes can be prepared with up to 95% enantioselectivity. This asymmetric procedure provides an efficient alternative route to prepare chiral β3-amino acids and alcohols. Copyright